ASD

GO:0043550 regulation of lipid kinase activity (19)

GeneInput weightStandardRank
PIK3R10.251150
CDC42--1138
IRS1--11374
RAC1--1617
VAV2--2850
VAV3--2908
PPP2R5A--3979
RBL2--5968
RB1--16804
CD81--112160
FGF2--13150
CCL19--14578
PIK3R5--19487
TGFB10.25120135
PDGFB--21071
NOD2--121514
CCL21--21829
CCR7--22367
RBL1--23048

Network

GO:0043550

Network
Enrichment
NameDescriptionExternal IDs
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
CDC42cell division cycle 42 Entrez:998  HPRD: 00309  HGNC: 1736  Ensembl: ENSG00000070831 
IRS1insulin receptor substrate 1 Entrez:3667  HPRD: 00943  HGNC: 6125 
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Entrez:5879  Ensembl: ENSG00000136238  HPRD: 03627  HGNC: 9801 
VAV2vav 2 guanine nucleotide exchange factor Entrez:7410  HGNC: 12658  HPRD: 02694  Ensembl: ENSG00000160293 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
CDC42cell division cycle 42
IRS1insulin receptor substrate 1
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
VAV2vav 2 guanine nucleotide exchange factor
Query geneGeneGene descriptionEdge score
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
CDC42CDC42cell division cycle 42
IRS1IRS1insulin receptor substrate 1
RAC1RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
VAV2VAV2vav 2 guanine nucleotide exchange factor

Troyanskaya Laboratory - Princeton University