ASD

GO:0046330 positive regulation of JNK cascade (38)

GeneInput weightStandardRank
PLCB1--148
HIPK2--1051
CDC42--1138
TAOK1--1336
FZD7--1357
TAOK20.2511633
MAP3K10--2968
WNT5A--3319
TAOK3--3466
WNT16--4117
AXIN1--14419
TRAF4--4556
IL1A--4651
EDA2R--4972
DUSP19--6060
WNT7B--7113
WNT7A--7312
IL1B--110818
FGF19--12130
MAP3K11--12938
TLR9--13360
CCL19--14578
TNF0.25115243
SDCBP--19967
F2RL1--19969
MAP4K2--20522
TIRAP--20658
RIPK2--20830
NOD2--121514
CCL21--21829
CCR7--22367
TLR3--22478
TPD52L1--22519
CD27--22836
MYD88--23106
NOD1--23388
CARD9--123577
DUSP22--24825

Network

GO:0046330

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
HIPK2homeodomain interacting protein kinase 2 Entrez:28996  HPRD: 06039  HGNC: 14402  Ensembl: ENSG00000064393 
CDC42cell division cycle 42 Entrez:998  HPRD: 00309  HGNC: 1736  Ensembl: ENSG00000070831 
TAOK1TAO kinase 1 Entrez:57551  HGNC: 29259  Ensembl: ENSG00000160551  HPRD: 15467 
FZD7frizzled family receptor 7 Entrez:8324  HGNC: 4045  HPRD: 04560  Ensembl: ENSG00000155760 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
HIPK2homeodomain interacting protein kinase 2
CDC42cell division cycle 42
TAOK1TAO kinase 1
FZD7frizzled family receptor 7
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
HIPK2HIPK2homeodomain interacting protein kinase 2
CDC42CDC42cell division cycle 42
TAOK1TAOK1TAO kinase 1
FZD7FZD7frizzled family receptor 7

Troyanskaya Laboratory - Princeton University