ASD

GO:0032933 SREBP-mediated signaling pathway (8)

GeneInput weightStandardRank
SREBF2--2312
INSIG1--2529
SCAP--2683
INSIG2--10252
ARHGEF10L--17881
SREBF1--19464
EIF2A--20947
LMNA--124292

Network

GO:0032933

Network
Enrichment
NameDescriptionExternal IDs
SREBF2sterol regulatory element binding transcription factor 2 Entrez:6721  HGNC: 11290  HPRD: 02726  Ensembl: ENSG00000198911 
INSIG1insulin induced gene 1 Entrez:3638  HPRD: 03633  HGNC: 6083  Ensembl: ENSG00000186480 
SCAPSREBF chaperone Entrez:22937  HPRD: 03300  HGNC: 30634  Ensembl: ENSG00000114650 
INSIG2insulin induced gene 2 Entrez:51141  Ensembl: ENSG00000125629  HGNC: 20452  HPRD: 16361 
ARHGEF10LRho guanine nucleotide exchange factor (GEF) 10-like Entrez:55160  Ensembl: ENSG00000074964  HGNC: 25540  HPRD: 07679 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SREBF2sterol regulatory element binding transcription factor 2
INSIG1insulin induced gene 1
SCAPSREBF chaperone
INSIG2insulin induced gene 2
ARHGEF10LRho guanine nucleotide exchange factor (GEF) 10-like
Query geneGeneGene descriptionEdge score
SREBF2SREBF2sterol regulatory element binding transcription factor 2
INSIG1INSIG1insulin induced gene 1
SCAPSCAPSREBF chaperone
INSIG2INSIG2insulin induced gene 2
ARHGEF10LARHGEF10LRho guanine nucleotide exchange factor (GEF) 10-like

Troyanskaya Laboratory - Princeton University