ASD

GO:0010822 positive regulation of mitochondrion organization (13)

GeneInput weightStandardRank
HRK--1660
MLLT11--1960
DNM1L--2558
BCL2L11--3469
MARCH5--6331
BMF--6376
BNIP3--6953
PMAIP1--7385
PINK1--118609
BBC3--20534
BIK--20799
BAK1--21229
BID--22640

Network

GO:0010822

Network
Enrichment
NameDescriptionExternal IDs
HRKharakiri, BCL2 interacting protein (contains only BH3 domain) Entrez:8739  HGNC: 5185  HPRD: 04581 
MLLT11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 Entrez:10962  HGNC: 16997  HPRD: 05251 
DNM1Ldynamin 1-like Entrez:10059  HGNC: 2973  HPRD: 04833  Ensembl: ENSG00000087470 
BCL2L11BCL2-like 11 (apoptosis facilitator) Entrez:10018  Ensembl: ENSG00000153094  HPRD: 04828  HGNC: 994 
MARCH5membrane-associated ring finger (C3HC4) 5 Entrez:54708  Ensembl: ENSG00000198060  HPRD: 07909  HGNC: 26025 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
HRKharakiri, BCL2 interacting protein (contains only BH3 domain)
MLLT11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
DNM1Ldynamin 1-like
BCL2L11BCL2-like 11 (apoptosis facilitator)
MARCH5membrane-associated ring finger (C3HC4) 5
Query geneGeneGene descriptionEdge score
HRKHRKharakiri, BCL2 interacting protein (contains only BH3 domain)
MLLT11MLLT11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
DNM1LDNM1Ldynamin 1-like
BCL2L11BCL2L11BCL2-like 11 (apoptosis facilitator)
MARCH5MARCH5membrane-associated ring finger (C3HC4) 5

Troyanskaya Laboratory - Princeton University