ASD

GO:0016441 posttranscriptional gene silencing (26)

GeneInput weightStandardRank
AGO2--490
ZCCHC11--737
DICER1--1762
SMAD3--823
TNRC6A--1752
SMAD1--1872
AGO3--2124
CELF1--2232
SMAD2--2694
AGO1--2764
AGO4--3370
RBM4--4069
LIN28B--5378
LIN28A--7070
DGCR8--8286
PRKRA--9728
WTIP--11726
SRRT--12400
SNIP1--12657
DROSHA--14199
AJUBA--18146
LIMD1--19839
RBM3--22670
MOV10--23619
CLP1--24100
TARBP2--24667

Network

GO:0016441

Network
Enrichment
NameDescriptionExternal IDs
AGO2argonaute RISC catalytic component 2 Entrez:27161  HGNC: 3263  HPRD: 06943  Ensembl: ENSG00000123908 
ZCCHC11zinc finger, CCHC domain containing 11 Entrez:23318  HGNC: 28981  Ensembl: ENSG00000134744  HPRD: 15700 
DICER1dicer 1, ribonuclease type III Entrez:23405  HGNC: 17098  Ensembl: ENSG00000100697  HPRD: 05875 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
TNRC6Atrinucleotide repeat containing 6A Entrez:27327  HPRD: 11640  HGNC: 11969  Ensembl: ENSG00000090905 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
AGO2argonaute RISC catalytic component 2
ZCCHC11zinc finger, CCHC domain containing 11
DICER1dicer 1, ribonuclease type III
SMAD3SMAD family member 3
TNRC6Atrinucleotide repeat containing 6A
Query geneGeneGene descriptionEdge score
AGO2AGO2argonaute RISC catalytic component 2
ZCCHC11ZCCHC11zinc finger, CCHC domain containing 11
DICER1DICER1dicer 1, ribonuclease type III
SMAD3SMAD3SMAD family member 3
TNRC6ATNRC6Atrinucleotide repeat containing 6A

Troyanskaya Laboratory - Princeton University