ASD

GO:0055117 regulation of cardiac muscle contraction (14)

GeneInput weightStandardRank
CACNA1G0.251443
HDAC4--696
NOS10.251853
RYR2--1959
ADORA1--960
SMAD7--1192
ADRA1A--1858
FKBP1B--2346
MEF2A--2837
RGS2--5095
NKX2-50.2518486
CAV3--115414
P2RX4--22325
CTGF--23607

Network

GO:0055117

Network
Enrichment
NameDescriptionExternal IDs
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit Entrez:8913  HPRD: 04961  HGNC: 1394  Ensembl: ENSG00000006283 
HDAC4histone deacetylase 4 Entrez:9759  Ensembl: ENSG00000068024  HPRD: 05610  HGNC: 14063 
NOS1nitric oxide synthase 1 (neuronal) Entrez:4842  HPRD: 01226  HGNC: 7872  Ensembl: ENSG00000089250 
RYR2ryanodine receptor 2 (cardiac) Entrez:6262  Ensembl: ENSG00000198626  HGNC: 10484  HPRD: 01619 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit
HDAC4histone deacetylase 4
NOS1nitric oxide synthase 1 (neuronal)
RYR2ryanodine receptor 2 (cardiac)
ADORA1adenosine A1 receptor
Query geneGeneGene descriptionEdge score
CACNA1GCACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit
HDAC4HDAC4histone deacetylase 4
NOS1NOS1nitric oxide synthase 1 (neuronal)
RYR2RYR2ryanodine receptor 2 (cardiac)
ADORA1ADORA1adenosine A1 receptor

Troyanskaya Laboratory - Princeton University