ASD

GO:0031098 stress-activated protein kinase signaling cascade (112)

GeneInput weightStandardRank
CREB1--100
MAPK10--1162
FGF12--263
RPS6KA5--359
MEF2C0.251428
MAP3K9--462
JUN--511
MAP3K12--533
RB1CC1--1534
SPAG9--558
MAP2K4--567
MAPK8IP1--1605
MINK1--606
FGF14--1668
RPS6KA20.251689
RPS6KA3--758
TAB2--785
MAP2K10.251907
MAPK1--1128
GAB1--1198
MAPK8--1214
MAP3K5--1220
MAP2K20.2511240
MAP3K7--1275
ATF2--1309
TNIK--1531
TAOK20.2511633
FOS--1680
MAPK11--1962
PKN1--1967
GPS1--2023
ELK1--2032
MAPK9--2237
MAPK8IP3--2274
DUSP6--2466
MAPKBP1--2654
MEF2A--2837
MAP3K13--2864
MAP4K5--2894
MAP3K10--2968
SH2D3C--3047
CRKL--3156
MAP3K2--3184
WNT5A--3319
MAP3K1--13381
TRIB1--3431
DAB2IP--3482
TAB3--3641
MAP3K4--3663
MAPKAPK2--3870
MAPK14--3975
DUSP4--4019
RBM4--4069
MAPK7--4384
AXIN1--14419
DUSP10--5172
MAP4K3--5481
TNFRSF19--5520
MAP2K7--5837
DUSP19--6060
MAPK30.2516426
UBC--6756
WNT7B--7113
TAB1--7218
WNT7A--7312
FGD4--17457
NPHS1--7618
DUSP3--8506
DAXX--8508
DUSP7--8625
CDC42EP5--9805
MAP2K6--10478
GFRAL--10777
TRAF6--11055
RHOC--11655
MAP3K11--12938
AGT--113305
MDFI--13519
DUSP9--13685
MAP2K3--13704
CCL19--14578
IRAK2--15024
GPS2--17956
ARHGEF6--19241
UBB--19448
ADORA2B--19522
BIRC7--19826
PTPLAD1--20272
MAP4K2--20522
RIPK2--20830
NOD2--121514
IRAK1--21640
MDFIC--21692
MAP4K1--22336
DBNL--22402
RIPK1--22681
CCM2--22768
MUL1--22953
IRAK4--23154
RPS6KA1--23184
NOD1--23388
SH2D3A--23424
STRADB--23510
IKBKG--123539
SYK--23906
MAPKAPK3--24170
MAP3K6--24220
ATF1--24277
RPS27A--24381
UBA52--24384
CRYAB--124965
CDK1--25053

Network

GO:0031098

Network
Enrichment
NameDescriptionExternal IDs
CREB1cAMP responsive element binding protein 1 Entrez:1385  HGNC: 2345  HPRD: 00442  Ensembl: ENSG00000118260 
MAPK10mitogen-activated protein kinase 10 Entrez:5602  HGNC: 6872  Ensembl: ENSG00000109339  HPRD: 04207 
FGF12fibroblast growth factor 12 Entrez:2257  HGNC: 3668  HPRD: 03303 
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5 Entrez:9252  Ensembl: ENSG00000100784  HPRD: 06789  HGNC: 10434 
MEF2Cmyocyte enhancer factor 2C Entrez:4208  HGNC: 6996  Ensembl: ENSG00000081189  HPRD: 02809 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CREB1cAMP responsive element binding protein 1
MAPK10mitogen-activated protein kinase 10
FGF12fibroblast growth factor 12
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5
MEF2Cmyocyte enhancer factor 2C
Query geneGeneGene descriptionEdge score
CREB1CREB1cAMP responsive element binding protein 1
MAPK10MAPK10mitogen-activated protein kinase 10
FGF12FGF12fibroblast growth factor 12
RPS6KA5RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 5
MEF2CMEF2Cmyocyte enhancer factor 2C

Troyanskaya Laboratory - Princeton University