ASD

GO:0032350 regulation of hormone metabolic process (21)

GeneInput weightStandardRank
IGF1R--252
CACNA1A--1270
NR3C1--496
HIF1A--1075
GATA3--2376
LHCGR0.2513057
TCF7L20.513548
CYP17A10.2513984
STUB1--4250
BMP6--4358
POR0.2515184
DKK3--5413
ATP1A10.2515927
TRERF1--6393
PAX8--16637
REST--9779
KDM1A--12183
GAL--13897
WNT4--21809
IGF20.25122401
ARNT--23123

Network

GO:0032350

Network
Enrichment
NameDescriptionExternal IDs
IGF1Rinsulin-like growth factor 1 receptor Entrez:3480  Ensembl: ENSG00000140443  HPRD: 00932  HGNC: 5465 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Entrez:3091  HGNC: 4910  Ensembl: ENSG00000100644  HPRD: 04517 
GATA3GATA binding protein 3 Entrez:2625  HGNC: 4172  Ensembl: ENSG00000107485  HPRD: 00572 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
IGF1Rinsulin-like growth factor 1 receptor
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
GATA3GATA binding protein 3
Query geneGeneGene descriptionEdge score
IGF1RIGF1Rinsulin-like growth factor 1 receptor
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
HIF1AHIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
GATA3GATA3GATA binding protein 3

Troyanskaya Laboratory - Princeton University