ASD

GO:0006940 regulation of smooth muscle contraction (39)

GeneInput weightStandardRank
MAP2K10.251907
ADORA1--960
CALCA--1013
ADRB1--1057
CHRNA3--1266
KCNB2--1576
CHRM3--1725
GUCY1A3--1997
ATP1A2--12247
GHSR0.2512467
SOD1--12702
CHRM2--2799
SRF--2841
TACR3--3564
FLT10.2513953
PROK2--14655
CHRNB4--4903
PTGS20.2515085
MYOCD--5907
OXTR0.516388
NMUR2--6430
PLCE1--6929
EDN1--9540
ADRA2B--10119
OXT0.25111176
TACR1--11618
NMS--12502
TNNI3--112758
EDN2--18677
P2RX1--19303
TBXA2R--19479
F2R--20036
NMU--22143
CNN1--23141
SPHK1--24069
PTGS1--24613
ADA0.5124751
LCK--24753
CAV1--125381

Network

GO:0006940

Network
Enrichment
NameDescriptionExternal IDs
MAP2K1mitogen-activated protein kinase kinase 1 Entrez:5604  HGNC: 6840  HPRD: 01469 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
CALCAcalcitonin-related polypeptide alpha Entrez:796  HGNC: 1437  HPRD: 00238  Ensembl: ENSG00000110680 
ADRB1adrenoceptor beta 1 Entrez:153  HGNC: 285  Ensembl: ENSG00000043591  HPRD: 00181 
CHRNA3cholinergic receptor, nicotinic, alpha 3 (neuronal) Entrez:1136  HGNC: 1957  HPRD: 07511  Ensembl: ENSG00000080644 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAP2K1mitogen-activated protein kinase kinase 1
ADORA1adenosine A1 receptor
CALCAcalcitonin-related polypeptide alpha
ADRB1adrenoceptor beta 1
CHRNA3cholinergic receptor, nicotinic, alpha 3 (neuronal)
Query geneGeneGene descriptionEdge score
MAP2K1MAP2K1mitogen-activated protein kinase kinase 1
ADORA1ADORA1adenosine A1 receptor
CALCACALCAcalcitonin-related polypeptide alpha
ADRB1ADRB1adrenoceptor beta 1
CHRNA3CHRNA3cholinergic receptor, nicotinic, alpha 3 (neuronal)

Troyanskaya Laboratory - Princeton University