ASD

GO:0008016 regulation of heart contraction (89)

GeneInput weightStandardRank
GNAO1--4
PIK3R10.251150
SP4--392
CACNA1G0.251443
KCNH2--1529
KCNIP2--572
CACNA1B--593
HDAC4--696
TAC10.251726
TGFB2--834
NOS10.251853
THRB--1881
RYR2--1959
ADORA1--960
CALCA--1013
ADRB1--1057
SMAD7--1192
CELF2--1303
EDN3--11577
CHRNA70.511837
ADRA1A--1858
AGTR20.2511955
ATP1A2--12247
KCNJ12--2338
FKBP1B--2346
CHRM2--2799
MEF2A--2837
SEMA3A--3494
HCN2--3542
TACR3--3564
DRD20.2513749
AVPR1A0.513803
CACNA1H1.013855
HBEGF--3865
GSK3A--4141
HOPX--4550
SCN5A--14668
IRX5--4848
TH0.2514933
ADRA1B0.2514946
RGS2--5095
GAA--15434
KCNE1L--5441
PDE5A--5684
ATP1A10.2515927
ADRBK1--6028
PLN0.2516577
ADORA3--6739
TNNT2--16745
APLN--7041
KCNE2--17178
KCNQ1--17724
FOXN4--7786
ADRA1D--7837
IL2--7838
NKX2-50.2518486
AVPR1B0.2518546
KCNE1--19266
EDN1--9540
GLP1R--9893
CSRP3--110846
EPAS1--10869
OXT0.25111176
CYP2J2--12046
DMPK0.25112484
PMCH--12542
IFNG--112827
MYH6--113823
GJA10.25113867
S100A1--14452
KCNG2--14521
CAV3--115414
PEBP1--15772
EDN2--18677
SREBF1--19464
MYH7--120417
MYL3--120524
CHRFAM7A--20694
DES--120845
SRI--21103
ADM--21106
P2RX4--22325
HSPB7--22630
ADRB20.25123251
CTGF--23607
TPM1--124247
ADA0.5124751
GLRX3--25135
MYL4--25690

Network

GO:0008016

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
SP4Sp4 transcription factor Entrez:6671  HGNC: 11209  Ensembl: ENSG00000105866  HPRD: 02764 
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit Entrez:8913  HPRD: 04961  HGNC: 1394  Ensembl: ENSG00000006283 
KCNH2potassium voltage-gated channel, subfamily H (eag-related), member 2 Entrez:3757  HPRD: 01069  HGNC: 6251  Ensembl: ENSG00000055118 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
SP4Sp4 transcription factor
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit
KCNH2potassium voltage-gated channel, subfamily H (eag-related), member 2
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
SP4SP4Sp4 transcription factor
CACNA1GCACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit
KCNH2KCNH2potassium voltage-gated channel, subfamily H (eag-related), member 2

Troyanskaya Laboratory - Princeton University