ASD

GO:0007265 Ras protein signal transduction (124)

GeneInput weightStandardRank
GNB1--24
KRAS--157
YWHAB0.251107
ARHGDIA--109
RAP2A--324
NF10.251372
ARHGAP5--464
SHC3--559
G3BP2--610
ARHGEF11--705
SOS1--1810
MAP2K10.251907
SHOC2--982
ULK1--1008
ADRB1--1057
MCF2L--1059
MAPK1--1128
SRGAP1--1215
MAP2K20.2511240
ADRA2A0.2511399
RALGDS--1603
CDH13--1692
VANGL2--1793
NISCH--1913
ELMO1--1914
MAPK11--1962
SHC2--2256
RHOA--2292
RAPGEF6--2744
IGF10.2512793
SRC--2825
GRB2--2962
RASGRP10.2513043
RHOB--3118
CRKL--3156
RAF10.2513236
ARHGAP1--3304
KSR1--3742
EDNRA--13857
MAPKAPK2--3870
MAPK14--3975
RREB1--4113
ARHGEF3--4159
CFL1--4162
RALA--4169
LIMK1--4265
ROCK1--4378
RAP2C--4477
ARHGAP29--4559
ABCA1--14703
MYO9B0.515005
HRAS0.2515086
ARHGAP6--5374
RALB--5931
FARP2--5987
CELSR1--6180
NGF0.2516229
AGTR1--16275
RHOG--6279
MAPK30.2516426
GNA13--6683
RB1--16804
ARHGDIG--6921
PLCE1--6929
PTH--6947
RGL2--6949
MRAS--7483
CDKN1A--7714
RHOJ--7924
USP8--8039
RASGRP3--8406
NTRK10.2518522
CDC42EP4--9514
CDC42EP5--9805
SHC1--10045
GRAP2--11440
RASGRP2--11775
WASF2--12417
RHOU--12495
FGF2--13150
G3BP1--13445
NRAS--114119
GNA12--14481
RSU1--14536
RTKN--14769
TAX1BP3--15553
DOK3--16204
TP530.25118277
APOA1--118958
IQGAP3--19438
ROPN1B--19629
SDCBP--19967
RRAS2--20019
APOC3--20262
PTPLAD1--20272
RAP2B--20526
SGSM3--20539
CDKN2A--120587
LAT--20987
MAPK12--21269
ARHGEF1--21297
CDC42EP1--21337
DHCR24--21358
ARHGAP4--21362
CNKSR1--21949
DOK2--22011
PLD1--22064
GRAP--22213
RASSF1--22228
DBNL--22402
CTNNAL1--22471
COL1A2--122629
RFXANK--122636
ARHGDIB--23104
APOE0.25123516
MAPKAPK3--24170
BRAP--24355
MAPK13--24490
DOK1--24800
CDK1--25053
RRAS--25111
RHOD--25163
CDK2--25445
CCNA2--25751

Network

GO:0007265

Network
Enrichment
NameDescriptionExternal IDs
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1 Entrez:2782  HGNC: 4396  HPRD: 00766  Ensembl: ENSG00000078369 
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
ARHGDIARho GDP dissociation inhibitor (GDI) alpha Entrez:396  HGNC: 678  Ensembl: ENSG00000141522  HPRD: 03565 
RAP2ARAP2A, member of RAS oncogene family Entrez:5911  HGNC: 9861  HPRD: 01547 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
KRASKirsten rat sarcoma viral oncogene homolog
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
ARHGDIARho GDP dissociation inhibitor (GDI) alpha
RAP2ARAP2A, member of RAS oncogene family
Query geneGeneGene descriptionEdge score
GNB1GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
KRASKRASKirsten rat sarcoma viral oncogene homolog
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
ARHGDIAARHGDIARho GDP dissociation inhibitor (GDI) alpha
RAP2ARAP2ARAP2A, member of RAS oncogene family

Troyanskaya Laboratory - Princeton University