ASD

GO:0070303 negative regulation of stress-activated protein kinase signaling cascade (22)

GeneInput weightStandardRank
MAPK8IP1--1605
NCOR1--1019
AKT10.2511020
ITCH--2932
TAOK3--3466
FOXO10.2513947
MEN1--14917
MECOM--4979
DUSP10--5172
DUSP19--6060
SFRP4--7310
DUSP3--8506
GSTP10.2518742
ZNF675--11676
GPS2--17956
F2RL1--19969
AMBP--20003
FKTN--120500
HDAC3--21702
IGBP1--25127
AIDA--25211
FOXM1--25656

Network

GO:0070303

Network
Enrichment
NameDescriptionExternal IDs
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1 Entrez:9479  HPRD: 05223  Ensembl: ENSG00000121653  HGNC: 6882 
NCOR1nuclear receptor corepressor 1 Entrez:9611  Ensembl: ENSG00000141027  HPRD: 02911  HGNC: 7672 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
ITCHitchy E3 ubiquitin protein ligase Entrez:83737  Ensembl: ENSG00000078747  HGNC: 13890 
TAOK3TAO kinase 3 Entrez:51347  HPRD: 11620  HGNC: 18133  Ensembl: ENSG00000135090 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1
NCOR1nuclear receptor corepressor 1
AKT1v-akt murine thymoma viral oncogene homolog 1
ITCHitchy E3 ubiquitin protein ligase
TAOK3TAO kinase 3
Query geneGeneGene descriptionEdge score
MAPK8IP1MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1
NCOR1NCOR1nuclear receptor corepressor 1
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
ITCHITCHitchy E3 ubiquitin protein ligase
TAOK3TAOK3TAO kinase 3

Troyanskaya Laboratory - Princeton University