ASD

GO:0031076 embryonic camera-type eye development (29)

GeneInput weightStandardRank
SOX11--96
LRP6--279
HIPK1--311
SP3--562
PAX2--653
PROX1--997
HIPK2--1051
BMP7--1137
TULP3--2770
TFAP2A--12923
WNT5A--3319
ALDH1A2--3771
WNT16--4117
SP1--4195
FGF10--14532
TH0.2514933
TWIST1--16980
IHH--17160
FRS2--7173
KDM2B--8359
RDH10--9300
LRP5--19420
SMO0.25110504
CRYAA--10509
STRA6--110685
NES--14479
ALDH1A3--21739
FZD5--23249
PPP1R13L--23749

Network

GO:0031076

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
HIPK1homeodomain interacting protein kinase 1 Entrez:204851  HGNC: 19006  Ensembl: ENSG00000163349  HPRD: 06418 
SP3Sp3 transcription factor Entrez:6670  HPRD: 03483  HGNC: 11208  Ensembl: ENSG00000172845 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
LRP6low density lipoprotein receptor-related protein 6
HIPK1homeodomain interacting protein kinase 1
SP3Sp3 transcription factor
PAX2paired box 2
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
LRP6LRP6low density lipoprotein receptor-related protein 6
HIPK1HIPK1homeodomain interacting protein kinase 1
SP3SP3Sp3 transcription factor
PAX2PAX2paired box 2

Troyanskaya Laboratory - Princeton University