ASD

GO:0045776 negative regulation of blood pressure (31)

GeneInput weightStandardRank
CNR10.25129
PIK3R10.251150
BMPR2--1281
NPY0.251592
ADORA1--960
CALCA--1013
ADRB1--1057
DRD50.2511103
ADRA1A--1858
AGTR20.2511955
ADRB3--12953
DRD20.2513749
PPARA--4177
ABAT0.2514348
DRD30.2514349
ADIPOQ0.2516032
APLN--7041
ADRA1D--7837
BDKRB2--10150
GUCA2B--10165
UCN--10358
OXT0.25111176
GCH10.25111867
PMCH--12542
VEGFC--12850
UTS2R--13768
ADM2--15255
BDKRB1--18217
RNPEP--19397
SOD2--22687
ADRB20.25123251

Network

GO:0045776

Network
Enrichment
NameDescriptionExternal IDs
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
NPYneuropeptide Y Entrez:4852  HGNC: 7955  HPRD: 01214  Ensembl: ENSG00000122585 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CNR1cannabinoid receptor 1 (brain)
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
NPYneuropeptide Y
ADORA1adenosine A1 receptor
Query geneGeneGene descriptionEdge score
CNR1CNR1cannabinoid receptor 1 (brain)
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
NPYNPYneuropeptide Y
ADORA1ADORA1adenosine A1 receptor

Troyanskaya Laboratory - Princeton University