ASD

GO:0043507 positive regulation of JUN kinase activity (48)

GeneInput weightStandardRank
MAP3K9--462
SPAG9--558
GAB1--1198
MAP3K5--1220
MAP3K7--1275
PKN1--1967
DVL3--2090
MAPK8IP3--2274
MAP4K5--2894
FZD10--2957
MAP3K10--2968
PTK2B--3063
MAP3K2--3184
WNT5A--3319
MAP3K1--13381
DAB2IP--3482
MAP3K4--3663
AXIN1--14419
PAK1--4940
TNFRSF11A--15293
MAP2K7--5837
DUSP19--6060
ZEB2--6361
DVL2--6546
WNT7B--7113
WNT7A--7312
FGD4--17457
DAXX--8508
EDN1--9540
IL1B--110818
TLR6--10981
TRAF6--11055
MAP3K11--12938
TLR9--13360
MDFI--13519
CCL19--14578
BIRC7--19826
PTPLAD1--20272
MAP4K2--20522
MDFIC--21692
MAP4K1--22336
DBNL--22402
RIPK1--22681
MUL1--22953
TRAF2--23686
SYK--23906
MAP3K6--24220
IL1RN0.25125385

Network

GO:0043507

Network
Enrichment
NameDescriptionExternal IDs
MAP3K9mitogen-activated protein kinase kinase kinase 9 Entrez:4293  Ensembl: ENSG00000006432  HGNC: 6861  HPRD: 15965 
SPAG9sperm associated antigen 9 Entrez:9043  HPRD: 10398  HGNC: 14524  Ensembl: ENSG00000008294 
GAB1GRB2-associated binding protein 1 Entrez:2549  HPRD: 05116  Ensembl: ENSG00000109458  HGNC: 4066 
MAP3K5mitogen-activated protein kinase kinase kinase 5 Entrez:4217  HPRD: 03904  HGNC: 6857  Ensembl: ENSG00000197442 
MAP3K7mitogen-activated protein kinase kinase kinase 7 Entrez:6885  HPRD: 04011  Ensembl: ENSG00000135341  HGNC: 6859 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAP3K9mitogen-activated protein kinase kinase kinase 9
SPAG9sperm associated antigen 9
GAB1GRB2-associated binding protein 1
MAP3K5mitogen-activated protein kinase kinase kinase 5
MAP3K7mitogen-activated protein kinase kinase kinase 7
Query geneGeneGene descriptionEdge score
MAP3K9MAP3K9mitogen-activated protein kinase kinase kinase 9
SPAG9SPAG9sperm associated antigen 9
GAB1GAB1GRB2-associated binding protein 1
MAP3K5MAP3K5mitogen-activated protein kinase kinase kinase 5
MAP3K7MAP3K7mitogen-activated protein kinase kinase kinase 7

Troyanskaya Laboratory - Princeton University