ASD

GO:0043467 regulation of generation of precursor metabolites and energy (40)

GeneInput weightStandardRank
PPP1CA--216
PGAM1--399
HDAC4--696
NCOR1--1019
AKT10.2511020
HIF1A--1075
DYRK2--1203
IRS2--11300
IRS1--11374
GRB10--1910
ATP7A--12483
GCK--12660
PPP1CB--2693
IGF10.2512793
DDIT4--3443
AKT2--13912
PPARA--4177
PRKAG2--14212
PRDM16--4345
ADRA1B0.2514946
INSR--15872
ENPP1--16091
SORBS1--6411
PTH--6947
PPP1R3D--7282
GAPDHS--8787
PRKACA--9630
C1QTNF2--10034
MLXIPL--11075
NOS20.25111577
PPP1R3E--12100
PPP1R3C--12887
ECD--19679
MTOR--21095
INS--122047
IGF20.25122401
ARNT--23123
PRKAG1--24404
CISD1--24683
PNPT1--25216

Network

GO:0043467

Network
Enrichment
NameDescriptionExternal IDs
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme Entrez:5499  Ensembl: ENSG00000172531  HPRD: 15942  HGNC: 9281 
PGAM1phosphoglycerate mutase 1 (brain) Entrez:5223  Ensembl: ENSG00000171314  HGNC: 8888  HPRD: 01392 
HDAC4histone deacetylase 4 Entrez:9759  Ensembl: ENSG00000068024  HPRD: 05610  HGNC: 14063 
NCOR1nuclear receptor corepressor 1 Entrez:9611  Ensembl: ENSG00000141027  HPRD: 02911  HGNC: 7672 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme
PGAM1phosphoglycerate mutase 1 (brain)
HDAC4histone deacetylase 4
NCOR1nuclear receptor corepressor 1
AKT1v-akt murine thymoma viral oncogene homolog 1
Query geneGeneGene descriptionEdge score
PPP1CAPPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme
PGAM1PGAM1phosphoglycerate mutase 1 (brain)
HDAC4HDAC4histone deacetylase 4
NCOR1NCOR1nuclear receptor corepressor 1
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1

Troyanskaya Laboratory - Princeton University