ASD

GO:0010953 regulation of protein maturation by peptide bond cleavage (14)

GeneInput weightStandardRank
CNTN2--674
RPS6KA20.251689
MASP1--2021
SERPINE2--3708
GLG1--4233
C6--8602
KLKB1--12910
F12--121126
ADAM8--21797
A2M--24058
THBS1--24444
SERPINE10.25125055
SERPING1--125126
PLGRKT--25130

Network

GO:0010953

Network
Enrichment
NameDescriptionExternal IDs
CNTN2contactin 2 (axonal) Entrez:6900  HGNC: 2172  Ensembl: ENSG00000184144  HPRD: 01826 
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2 Entrez:6196  Ensembl: ENSG00000071242  HPRD: 03403  HGNC: 10431 
MASP1mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) Entrez:5648  HPRD: 02749  HGNC: 6901  Ensembl: ENSG00000127241 
SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 Entrez:5270  Ensembl: ENSG00000135919  HGNC: 8951  HPRD: 01510 
GLG1golgi glycoprotein 1 Entrez:2734  HPRD: 02855  HGNC: 4316 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CNTN2contactin 2 (axonal)
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2
MASP1mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
GLG1golgi glycoprotein 1
Query geneGeneGene descriptionEdge score
CNTN2CNTN2contactin 2 (axonal)
RPS6KA2RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2
MASP1MASP1mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
SERPINE2SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
GLG1GLG1golgi glycoprotein 1

Troyanskaya Laboratory - Princeton University