ASD

GO:0048661 positive regulation of smooth muscle cell proliferation (35)

GeneInput weightStandardRank
JUN--511
NPY5R0.251725
HIF1A--1075
CX3CL1--1199
RPS6KB1--1521
CDH13--1692
NOX1--1924
ID2--2154
STAT5B--2593
IGF10.2512793
HBEGF--3865
FLT10.2513953
VEGFA0.2514087
S1PR1--4301
CALCRL0.2514392
PTGS20.2515085
BMP4--16499
EREG--9052
EDN1--9540
SHC1--10045
IL6--112695
IL13--12888
TNF0.25115243
ELANE--115526
IL6R--19897
PDGFB--21071
MNAT1--21615
AGER--22895
CCL5--23042
MYD88--23106
IRAK4--23154
TGM2--23204
PDGFRB--23242
AIF1--23667
HMOX1--23938

Network

GO:0048661

Network
Enrichment
NameDescriptionExternal IDs
JUNjun proto-oncogene Entrez:3725  HGNC: 6204  HPRD: 01302  Ensembl: ENSG00000177606 
NPY5Rneuropeptide Y receptor Y5 Entrez:4889  HPRD: 03591  Ensembl: ENSG00000164129  HGNC: 7958 
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Entrez:3091  HGNC: 4910  Ensembl: ENSG00000100644  HPRD: 04517 
CX3CL1chemokine (C-X3-C motif) ligand 1 Entrez:6376  HGNC: 10647  HPRD: 03529  Ensembl: ENSG00000006210 
RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1 Entrez:6198  Ensembl: ENSG00000108443  HGNC: 10436  HPRD: 10202 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
JUNjun proto-oncogene
NPY5Rneuropeptide Y receptor Y5
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
CX3CL1chemokine (C-X3-C motif) ligand 1
RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1
Query geneGeneGene descriptionEdge score
JUNJUNjun proto-oncogene
NPY5RNPY5Rneuropeptide Y receptor Y5
HIF1AHIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
CX3CL1CX3CL1chemokine (C-X3-C motif) ligand 1
RPS6KB1RPS6KB1ribosomal protein S6 kinase, 70kDa, polypeptide 1

Troyanskaya Laboratory - Princeton University