ASD

GO:0008543 fibroblast growth factor receptor signaling pathway (78)

GeneInput weightStandardRank
CREB1--100
PIK3R10.251150
RAB14--213
FGFR2--1237
FGF9--262
PHLPP1--332
GSK3B--427
FIBP--523
RICTOR--537
SOS1--1810
SHOC2--982
AKT10.2511020
FOXO3--1056
CDKN1B--1162
GAB1--1198
BAD--1290
IRS2--11300
PIK3CA0.2511362
IRS1--11374
PTEN1.011389
PDPK1--1740
FGF1--1892
FGFR1--2262
FGF5--2327
FGF7--2591
FGFR3--12640
SRC--2825
GRB2--2962
FGF23--13888
KL--3938
FOXO10.2513947
GSK3A--4141
FGF20--4263
FRS3--4312
FGF10--14532
FGF3--4687
PLCG1--4744
CEP57--4857
FGF4--4938
MLST8--5028
FGF17--5072
NDST1--5114
PIK3R2--5198
NOG--15439
INSR--15872
PIK3R4--6073
FGF18--6382
MDM2--6675
FRS2--7173
CDKN1A--7714
PTPN11--17735
FGF16--8467
FGF8--18543
KLB--9187
TSC20.2519351
PIK3C3--9358
FOXO4--9362
SHC1--10045
FGFRL1--10721
PIK3CB--11542
FGF19--12130
NR4A1--12498
FGF2--13150
FGF22--13277
TLR9--13360
AKT1S1--13569
FGF6--15185
MAPKAP1--20094
TRIB3--20863
CASP90.25121044
MTOR--21095
INS--122047
KIF16B--22922
RPS6KB2--23226
FGFR4--23965
THEM4--24011
CHUK--24756
DOK1--24800

Network

GO:0008543

Network
Enrichment
NameDescriptionExternal IDs
CREB1cAMP responsive element binding protein 1 Entrez:1385  HGNC: 2345  HPRD: 00442  Ensembl: ENSG00000118260 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
RAB14RAB14, member RAS oncogene family Entrez:51552  HPRD: 06693  Ensembl: ENSG00000119396  HGNC: 16524 
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
FGF9fibroblast growth factor 9 Entrez:2254  HPRD: 02951  HGNC: 3687  Ensembl: ENSG00000102678 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CREB1cAMP responsive element binding protein 1
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RAB14RAB14, member RAS oncogene family
FGFR2fibroblast growth factor receptor 2
FGF9fibroblast growth factor 9
Query geneGeneGene descriptionEdge score
CREB1CREB1cAMP responsive element binding protein 1
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RAB14RAB14RAB14, member RAS oncogene family
FGFR2FGFR2fibroblast growth factor receptor 2
FGF9FGF9fibroblast growth factor 9

Troyanskaya Laboratory - Princeton University