ASD

GO:0007492 endoderm development (42)

GeneInput weightStandardRank
SOX2--1200
SMAD4--821
SMAD3--823
BMPR1A--1140
PTHLH--11993
DUSP5--2022
EPB41L5--2335
LHX1--2560
FOXA2--2645
SMAD2--2694
NOTCH1--12865
HOXC11--2906
NODAL--13149
WNT8B--3407
DUSP1--3785
DUSP4--4019
SOX17--4024
NANOG--4083
NKX2-1--4142
EXT10.2514780
SOX7--6117
WNT8A--7814
WNT11--7820
WNT9B--8217
ARC0.2518587
DUSP2--8596
TBX20--18764
CTNNB10.519066
MIXL1--9839
HNF1B--19881
GDF3--110819
GATA6--110828
DKK1--11567
PAX9--111940
GATA4--112466
EOMES--12952
WNT9A--13365
POU5F1--19704
TGFB10.25120135
WNT4--21809
KIF16B--22922
LAMC1--23363

Network

GO:0007492

Network
Enrichment
NameDescriptionExternal IDs
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
SMAD4SMAD family member 4 Entrez:4089  Ensembl: ENSG00000141646  HGNC: 6770  HPRD: 02995 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
BMPR1Abone morphogenetic protein receptor, type IA Entrez:657  HGNC: 1076  Ensembl: ENSG00000107779  HPRD: 03192 
PTHLHparathyroid hormone-like hormone Entrez:5744  HPRD: 01348  Ensembl: ENSG00000087494  HGNC: 9607 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX2SRY (sex determining region Y)-box 2
SMAD4SMAD family member 4
SMAD3SMAD family member 3
BMPR1Abone morphogenetic protein receptor, type IA
PTHLHparathyroid hormone-like hormone
Query geneGeneGene descriptionEdge score
SOX2SOX2SRY (sex determining region Y)-box 2
SMAD4SMAD4SMAD family member 4
SMAD3SMAD3SMAD family member 3
BMPR1ABMPR1Abone morphogenetic protein receptor, type IA
PTHLHPTHLHparathyroid hormone-like hormone

Troyanskaya Laboratory - Princeton University