ASD

GO:0014072 response to isoquinoline alkaloid (23)

GeneInput weightStandardRank
GNAO1--4
CNR10.25129
PRKCE--204
GRIN1--294
PPP2R2A--714
TAC10.251726
PCSK1--898
RELA--1142
TAC3--3251
TACR3--3564
DRD20.2513749
CYP19A10.2513823
EDNRA--13857
DRD30.2514349
PLCG1--4744
ADRA1B0.2514946
PEA15--5442
GHR--110098
IL1B--110818
TACR1--11618
SRR--20837
CCL5--23042
ADA0.5124751

Network

GO:0014072

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
PRKCEprotein kinase C, epsilon Entrez:5581  HPRD: 01500  HGNC: 9401  Ensembl: ENSG00000171132 
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1 Entrez:2902  HGNC: 4584  HPRD: 15926  Ensembl: ENSG00000176884 
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha Entrez:5520  Ensembl: ENSG00000221914  HPRD: 09223  HGNC: 9304 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1cannabinoid receptor 1 (brain)
PRKCEprotein kinase C, epsilon
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1
PPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
CNR1CNR1cannabinoid receptor 1 (brain)
PRKCEPRKCEprotein kinase C, epsilon
GRIN1GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1
PPP2R2APPP2R2Aprotein phosphatase 2, regulatory subunit B, alpha

Troyanskaya Laboratory - Princeton University