ASD

GO:0090199 regulation of release of cytochrome c from mitochondria (16)

GeneInput weightStandardRank
PARK20.251952
HRK--1660
MLLT11--1960
PSMD10--2412
BCL2L11--3469
BMF--6376
BCL2L1--6563
BNIP3--6953
PMAIP1--7385
AVP--113439
PINK1--118609
BBC3--20534
BIK--20799
BAK1--21229
BID--22640
FXN--125604

Network

GO:0090199

Network
Enrichment
NameDescriptionExternal IDs
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin) Entrez:5071  HPRD: 03967  HGNC: 8607  Ensembl: ENSG00000185345 
HRKharakiri, BCL2 interacting protein (contains only BH3 domain) Entrez:8739  HGNC: 5185  HPRD: 04581 
MLLT11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 Entrez:10962  HGNC: 16997  HPRD: 05251 
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 Entrez:5716  HPRD: 04594  HGNC: 9555  Ensembl: ENSG00000101843 
BCL2L11BCL2-like 11 (apoptosis facilitator) Entrez:10018  Ensembl: ENSG00000153094  HPRD: 04828  HGNC: 994 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
HRKharakiri, BCL2 interacting protein (contains only BH3 domain)
MLLT11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
BCL2L11BCL2-like 11 (apoptosis facilitator)
Query geneGeneGene descriptionEdge score
PARK2PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
HRKHRKharakiri, BCL2 interacting protein (contains only BH3 domain)
MLLT11MLLT11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
PSMD10PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
BCL2L11BCL2L11BCL2-like 11 (apoptosis facilitator)

Troyanskaya Laboratory - Princeton University