ASD

GO:0040019 positive regulation of embryonic development (7)

GeneInput weightStandardRank
PLCB1--148
MEG3--238
AMOT--1325
OTX2--11916
LHX1--2560
FOXA2--2645
RBM19--9608

Network

GO:0040019

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
AMOTangiomotin Entrez:154796  HGNC: 17810  Ensembl: ENSG00000126016  HPRD: 02327 
OTX2orthodenticle homeobox 2 Entrez:5015  HGNC: 8522  HPRD: 07190  Ensembl: ENSG00000165588 
LHX1LIM homeobox 1 Entrez:3975  HGNC: 6593  HPRD: 09067  Ensembl: ENSG00000132130 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
MEG3maternally expressed 3 (non-protein coding)
AMOTangiomotin
OTX2orthodenticle homeobox 2
LHX1LIM homeobox 1
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
MEG3MEG3maternally expressed 3 (non-protein coding)
AMOTAMOTangiomotin
OTX2OTX2orthodenticle homeobox 2
LHX1LHX1LIM homeobox 1

Troyanskaya Laboratory - Princeton University