ASD

GO:0032414 positive regulation of ion transmembrane transporter activity (22)

GeneInput weightStandardRank
CALM3--352
CALM1--1029
ADRB1--1057
ACTN4--12685
WNK30.2512810
CALM2--2814
TRPC60.512954
HOMER10.2513402
STIM2--3653
PLCG1--4744
DRD40.2517021
CXCL12--7802
EFCAB4B--7947
NKX2-50.2518486
GLP1R--9893
CCKAR--11747
AGT--113305
STIM1--17385
ZP3--17443
VDR--21837
ADRB20.25123251
PLCG2--24731

Network

GO:0032414

Network
Enrichment
NameDescriptionExternal IDs
CALM3calmodulin 3 (phosphorylase kinase, delta) Entrez:808  HPRD: 00243  Ensembl: ENSG00000160014  HGNC: 1449 
CALM1calmodulin 1 (phosphorylase kinase, delta) Entrez:801  HPRD: 00241  HGNC: 1442  Ensembl: ENSG00000198668 
ADRB1adrenoceptor beta 1 Entrez:153  HGNC: 285  Ensembl: ENSG00000043591  HPRD: 00181 
ACTN4actinin, alpha 4 Entrez:81  HPRD: 05222  HGNC: 166 
WNK3WNK lysine deficient protein kinase 3 Entrez:65267  HGNC: 14543  HPRD: 02289  Ensembl: ENSG00000196632 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CALM3calmodulin 3 (phosphorylase kinase, delta)
CALM1calmodulin 1 (phosphorylase kinase, delta)
ADRB1adrenoceptor beta 1
ACTN4actinin, alpha 4
WNK3WNK lysine deficient protein kinase 3
Query geneGeneGene descriptionEdge score
CALM3CALM3calmodulin 3 (phosphorylase kinase, delta)
CALM1CALM1calmodulin 1 (phosphorylase kinase, delta)
ADRB1ADRB1adrenoceptor beta 1
ACTN4ACTN4actinin, alpha 4
WNK3WNK3WNK lysine deficient protein kinase 3

Troyanskaya Laboratory - Princeton University