ASD

GO:0045921 positive regulation of exocytosis (20)

GeneInput weightStandardRank
PLCB1--148
CADPS--133
STX1A0.251512
CRHR1--589
NCS1--2628
SCAMP50.2512682
GLRA1--2965
CDK50.2513194
GAB2--3496
STXBP5--3733
CACNA1H1.013855
DOC2B--11084
MS4A2--13136
ZP4--14747
ZP3--17443
F2RL1--19969
UNC13D--121158
FCER1G--21507
PLD2--22908
SYK--23906

Network

GO:0045921

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
CADPSCa++-dependent secretion activator Entrez:8618  Ensembl: ENSG00000163618  HGNC: 1426  HPRD: 05236 
STX1Asyntaxin 1A (brain) Entrez:6804  Ensembl: ENSG00000106089  HGNC: 11433  HPRD: 01721 
CRHR1corticotropin releasing hormone receptor 1 Entrez:1394  Ensembl: ENSG00000120088  HGNC: 2357  HPRD: 08830 
NCS1neuronal calcium sensor 1 Entrez:23413  HPRD: 04500  Ensembl: ENSG00000107130  HGNC: 3953 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCa++-dependent secretion activator
STX1Asyntaxin 1A (brain)
CRHR1corticotropin releasing hormone receptor 1
NCS1neuronal calcium sensor 1
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CADPSCADPSCa++-dependent secretion activator
STX1ASTX1Asyntaxin 1A (brain)
CRHR1CRHR1corticotropin releasing hormone receptor 1
NCS1NCS1neuronal calcium sensor 1

Troyanskaya Laboratory - Princeton University