ASD

GO:2000147 positive regulation of cell motility (170)

GeneInput weightStandardRank
ERBB40.25186
PIK3R10.251150
IGF1R--252
APC0.251266
BMPR2--1281
PDGFRA--1320
SPAG9--558
TAC10.251726
SMAD3--823
TGFB2--834
DRD10.251899
RAPGEF40.251904
MAP2K10.251907
PRKD1--909
SOX9--1970
PROX1--997
AKT10.2511020
PRKCA--1027
HIF1A--1075
MAPK1--1128
CX3CL1--1199
IRS2--11300
AMOT--1325
IRS1--11374
ADRA2A0.2511399
LEF1--1499
RPS6KB1--1521
EDN3--11577
CDH13--1692
ONECUT2--1700
FGF1--1892
MADCAM1--2071
PRKD2--2228
EPB41L5--2335
GATA3--2376
EGFR--12546
FGF7--2591
PTP4A1--2601
MIA3--2741
IGF10.2512793
PTK2B--3063
HDAC9--3228
WNT5A--3319
FOXF1--13518
IL6ST--3678
PDGFA--3731
EDNRA--13857
HBEGF--3865
ITGB1--3903
AKT2--13912
FLT10.2513953
VEGFA0.2514087
LPAR1--4170
ANGPT1--4182
S1PR1--4301
FGF10--14532
FURIN--4605
PLCG1--4744
KDR0.2514854
SYNE2--14999
ZNF703--5031
PTGS20.2515085
ANGPTL3--5089
ADAM17--5323
F7--5465
INSR--15872
ETS1--5943
TDGF1--6132
BMP4--16499
CSF1--6542
FIGF--6702
TWIST1--16980
ILK--7305
CXCL12--7802
XCL1--7819
WNT11--7820
CXCL13--8148
SNAI1--9198
CREB3--9450
EDN1--9540
CCL11--9615
TRIM320.2519794
FOXC2--10175
ANGPT4--10249
PPAP2B--10628
F3--10889
ROR2--111002
IL23A--11134
TACR1--11618
RHOC--11655
ITGB30.5111817
VEGFB--11980
BCAR1--12026
IL6--112695
PLA2G7--12734
VEGFC--12850
PODXL--13125
FGF2--13150
AAMP--13187
VTN--13271
AGT--113305
THBS4--13380
SCARB1--13530
SELP--13751
CCL19--14578
SELE--14642
CMKLR1--14683
HDAC7--14702
ALOX12--14851
WNT5B--15534
IL8--15864
HDAC6--16779
ZP3--17443
BDKRB1--18217
EDN2--18677
CXCL16--18933
PDPN--19764
IL6R--19897
CBLL1--19963
F2RL1--19969
RRAS2--20019
F2R--20036
TGFB10.25120135
CORO1A--20339
GRB7--20514
LBP--20559
TIRAP--20658
ADAM10--20986
TRIP6--21037
ABCC1--21066
CXCL10--21069
PDGFB--21071
SRPX2--21503
ADAM8--21797
CCL21--21829
CCL24--21868
INS--122047
PLD1--22064
S100A7--22068
F10--22126
SUN2--22170
VIL10.5122243
CCR7--22367
CYR61--22574
CCL26--22814
AGER--22895
PLD2--22908
ANXA3--22980
CCL5--23042
PDGFRB--23242
GNB2L1--23282
CCR2--23296
C3AR1--23652
AIF1--23667
ICAM1--23720
NCKAP1L--23771
SNAI2--123962
CD74--24030
SPHK1--24069
P2RY2--24088
COL1A1--124140
MMP9--24369
THBS1--24444
LAMB10.5124677
FGFR1OP--24857
SERPINE10.25125055
COL18A1--25059
S100A14--25078
RARRES2--25092
ADAM9--125221

Network

GO:2000147

Network
Enrichment
NameDescriptionExternal IDs
ERBB4v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 Entrez:2066  HGNC: 3432  HPRD: 02767  Ensembl: ENSG00000178568 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
IGF1Rinsulin-like growth factor 1 receptor Entrez:3480  Ensembl: ENSG00000140443  HPRD: 00932  HGNC: 5465 
APCadenomatous polyposis coli Entrez:324  HGNC: 583  HPRD: 01439  Ensembl: ENSG00000134982 
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ERBB4v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
IGF1Rinsulin-like growth factor 1 receptor
APCadenomatous polyposis coli
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
Query geneGeneGene descriptionEdge score
ERBB4ERBB4v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
IGF1RIGF1Rinsulin-like growth factor 1 receptor
APCAPCadenomatous polyposis coli
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)

Troyanskaya Laboratory - Princeton University