ASD

GO:0050821 protein stabilization (47)

GeneInput weightStandardRank
GNAQ--189
FBXW7--198
SOX4--250
SMAD3--823
SMAD7--1192
BAG6--1305
PTEN1.011389
WNT10B--1517
PPARGC1A--1909
GAPDH--2661
MSX1--13127
PARK7--13322
HCFC1--3371
USP2--3856
SOX17--4024
UBE2B--4057
FLNA--14285
HSPD1--14908
STX12--5317
GPIHBP1--5357
CPN2--5804
TCF3--6420
PRKCD--6504
DSG1--7167
TBRG1--7747
MDM4--7770
MORC3--8413
A1CF--10245
PPAP2B--10628
VHL--111546
NAPG--12226
WFS10.25112793
HPS4--12942
COG3--15178
DSC3--16265
AHSP--17874
APOA1--118958
PEX6--19177
CDKN2A--120587
CALR--22152
COG7--122224
RASSF1--22228
IFT46--22230
GTPBP4--23572
PML--25277
CLU--25437
DNAJA3--25610

Network

GO:0050821

Network
Enrichment
NameDescriptionExternal IDs
GNAQguanine nucleotide binding protein (G protein), q polypeptide Entrez:2776  HGNC: 4390  HPRD: 02998 
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HPRD: 05888  Ensembl: ENSG00000109670  HGNC: 16712 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
SMAD7SMAD family member 7 Entrez:4092  HPRD: 04241  HGNC: 6773  Ensembl: ENSG00000101665 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAQguanine nucleotide binding protein (G protein), q polypeptide
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
SOX4SRY (sex determining region Y)-box 4
SMAD3SMAD family member 3
SMAD7SMAD family member 7
Query geneGeneGene descriptionEdge score
GNAQGNAQguanine nucleotide binding protein (G protein), q polypeptide
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
SOX4SOX4SRY (sex determining region Y)-box 4
SMAD3SMAD3SMAD family member 3
SMAD7SMAD7SMAD family member 7

Troyanskaya Laboratory - Princeton University