ASD

GO:0031400 negative regulation of protein modification process (168)

GeneInput weightStandardRank
PPP2CA--20
SET--31
PSMA1--58
PSMD14--104
YWHAB0.251107
PSMA4--166
PSMB3--234
SOX4--250
LRP6--279
PSMA5--284
PSMD8--371
SFRP1--387
PSMA3--460
PSMB1--501
JUN--511
SLIT2--659
SNCA--1667
PSMC6--679
PSMD6--688
MGEA5--732
PSMB7--745
CTBP1--760
TSC10.251790
PSMC2--815
SMAD3--823
JARID2--946
PARK20.251952
PSMD11--967
PRKCZ--991
YWHAE--995
PSMB4--1091
PPP2R1A--1163
PSMD1--1168
PSMA7--1174
SMAD7--1192
BAG5--1229
PSMC4--1269
PSMC1--1296
PTEN1.011389
PRKCG--11483
PSMA6--1510
PSMD12--1573
PSMB6--1607
PSMD2--1706
BUB3--1718
N4BP1--1749
PSMC5--1897
PSMD3--2008
PSMD4--2087
PSMC3--2240
BCOR--12290
SMAD6--2305
PSMD10--2412
DUSP6--2466
PSMD7--2481
PPP2R4--2609
PSMA2--2699
SKI--2904
FZR1--2920
PSMD13--3051
CDK50.2513194
USP44--3406
INPP5J--3690
UBE2B--4057
AKAP1--4078
VPS28--4150
MAS1--4244
LIMK1--4265
WNT1--4383
TNFAIP3--4469
MEN1--14917
ANAPC2--5008
PAX50.515041
SFRP2--5252
PRNP--15418
RASD2--5562
INSR--15872
NF2--15991
DNAJB2--6026
ADIPOQ0.2516032
ENPP1--16091
HHATL--6451
PRKCD--6504
ERRFI1--6649
UBC--6756
TWIST1--16980
PPEF2--7509
USP4--7808
IL2--7838
G6PD--7945
UBE2E1--7950
MET1.018002
SOCS1--9583
CDC27--9665
BDKRB2--10150
PPAP2B--10628
ARRB2--10647
ATG5--11069
MLXIPL--11075
TAF7--11434
DKK1--11567
IRF1--111641
PSMB2--11986
GCLC--12360
FOXP3--112457
DNMT1--13233
FAM129A--13686
MAD2L2--13802
PSMD9--13911
PSME2--14327
DNMT3B--14663
CDC23--14728
ANAPC11--14928
PEBP1--15772
BDKRB1--18217
PSEN1--18523
DVL1P1--18731
CNKSR3--19160
UBB--19448
NLRP12--19807
PSMD5--19823
ARRB1--19906
SAMSN1--19930
TGFB10.25120135
CDKN2A--120587
ACER2--20862
PSME1--21072
ANAPC10--21179
PSMB9--21373
PSMB10--21853
PSMB8--22146
PSME3--22162
CDC26--22265
IGFBP3--22342
PSMF1--22424
IBTK--22790
HNF4A--122965
PSEN2--23095
GTPBP4--23572
UBXN1--23735
TINF2--24033
INPP5K--24055
PTPN6--24184
WWTR1--24317
RPS27A--24381
UBA52--24384
ANAPC4--24419
IMPACT--24430
BRCA1--124573
ANAPC7--24632
ENG--124746
TRIM21--24895
UBE2D1--24988
CDC16--24989
IGBP1--25127
CCNB1--25174
ANAPC1--25203
PSMB5--25250
PML--25277
MAD2L1--25321
ANAPC5--25367
CAV1--125381
FBXO5--25488
CDC20--25608
UBE2C--25614
UFL1--25631
DNAJC10--25717
BUB1B--125766

Network

GO:0031400

Network
Enrichment
NameDescriptionExternal IDs
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme Entrez:5515  HGNC: 9299  HPRD: 08912 
SETSET nuclear oncogene Entrez:6418  HGNC: 10760  HPRD: 09023  Ensembl: ENSG00000119335 
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
SETSET nuclear oncogene
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
Query geneGeneGene descriptionEdge score
PPP2CAPPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
SETSETSET nuclear oncogene
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

Troyanskaya Laboratory - Princeton University