ASD

GO:0010817 regulation of hormone levels (192)

GeneInput weightStandardRank
SNAP250.25126
NEUROD1--1127
PCSK2--217
MEG3--238
YWHAZ0.251269
CACNA1A--1270
RIMS2--282
PDGFRA--1320
NR3C1--496
CRH--563
DIO2--625
CAMK2G--798
PCSK1--898
RAPGEF40.251904
LRP20.251984
MED1--1034
PCSK6--1035
SCG50.2511173
SCHIP1--1178
EDN3--11577
ACVR2B--11676
CYP26B1--1734
VGF0.2511782
ESR10.2511791
CARTPT0.2511957
FOXA1--1990
YWHAH--2009
PCSK1N--2078
CPE--2149
FZD4--12229
CGA0.2512258
FKBP1B--2346
TSHB--2368
ASMTL--2405
GHSR0.2512467
STAT5B--2593
CRHBP--2688
SMAD2--2694
CPLX1--2778
TIPARP--2888
SAFB--2899
TBX3--2958
CYP26A1--3009
RBP4--3448
SLC30A8--13644
FOXE3--13688
ALDH1A2--3771
CRYM--3820
CYP19A10.2513823
MC4R0.2513850
CACNA1H1.013855
FOXE1--13900
PLEKHA1--3930
CYP17A10.2513984
DIO3--4145
GHRHR--4237
CPLX3--4281
FURIN--4605
SOX8--4609
PRLHR--4669
CORIN--4683
HSD3B2--4818
TH0.2514933
SRD5A10.2514966
LRAT--15055
CYP1A10.2515067
SRD5A20.2515363
AANAT0.2515448
ADH7--5526
CHST8--5529
AKR1D1--15546
HSD3B1--5560
TPH20.2515693
CYP26C1--5830
CHST9--5902
DDC0.2515929
NGF0.2516229
SULT1E1--6341
TPO--16347
ALDH8A1--6351
SLC18A2--6423
TPH10.2516460
CYP11B10.2516613
SDR16C5--6965
UGT1A8--6979
REN--17086
DUOX1--7090
GHRH--7478
RDH12--17538
SLC5A5--17711
PDX1--17958
CYP11A10.2518063
PNMT--8605
STAR--8811
HSD11B10.2518910
AKR1C4--8941
GHRL0.2519242
RDH10--9300
CGB7--9343
SHBG0.2519419
HSD17B6--9498
EDN1--9540
GCNT4--9812
HNF1B--19881
HSD11B2--9892
CYP3A4--9925
HSD17B30.2519988
ACE--10304
LYN--10336
RDH8--10339
ECE2--10348
DBH0.25110495
BCO2--10506
PCSK7--10515
ASMT0.25110532
RBP1--10542
SULT1B1--10710
KLK6--10748
FFAR4--10968
ACE2--11390
DHRS2--11471
IYD--11474
DIO1--11488
AFP--11538
DUOX2--111733
CCKAR--11747
ADH4--11856
LEP0.25111864
UGT2B4--11987
LY6E--12003
SERPINA6--12381
FAM3B--12628
IL6--112695
FSHB0.25112923
MAFA--13014
PCSK5--13062
FGF2--13150
AGT--113305
CYP21A20.25113362
GPR119--13402
COMT0.25113475
SCARB1--13530
CYP11B2--13660
GAL--13897
DGAT1--14036
CGB5--14205
SLCO4A1--14525
HNF1A--114631
POMC0.25114990
UGT2B11--15201
CGB8--15211
SGPL1--15362
INHBA--16974
IQCJ-SCHIP1--17789
UGT1A7--18533
TG--18556
SHH--118571
DHRS9--18976
UGT1A9--19030
SLC22A1--19237
LHB0.25119520
HSD17B1--19915
SRD5A3--120013
BACE2--20446
EIF2AK3--20456
ECE1--120540
CYB5R4--20918
ADM--21106
RDH11--21301
HSD17B20.25121493
EXOC3L1--21538
ALDH1A3--21739
WNT4--21809
CGB--22000
STARD5--22138
AKR1B1--22159
CYP1B10.25122210
UGT1A1--122467
CRABP2--22763
ANXA10.5122810
HSD17B11--22986
ALDH9A1--23032
UGT1A3--23330
LTBP4--25003
DHRS3--25202
BCAT2--25326
ATP6AP2--25361
IL1RN0.25125385
HSD17B8--25429
IDE--25443
RETSAT--25533
SCPEP1--25678

Network

GO:0010817

Network
Enrichment
NameDescriptionExternal IDs
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
NEUROD1neuronal differentiation 1 Entrez:4760  HPRD: 03428  HGNC: 7762  Ensembl: ENSG00000162992 
PCSK2proprotein convertase subtilisin/kexin type 2 Entrez:5126  Ensembl: ENSG00000125851  HGNC: 8744  HPRD: 01202 
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide Entrez:7534  HPRD: 03183  Ensembl: ENSG00000164924  HGNC: 12855 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SNAP25synaptosomal-associated protein, 25kDa
NEUROD1neuronal differentiation 1
PCSK2proprotein convertase subtilisin/kexin type 2
MEG3maternally expressed 3 (non-protein coding)
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
Query geneGeneGene descriptionEdge score
SNAP25SNAP25synaptosomal-associated protein, 25kDa
NEUROD1NEUROD1neuronal differentiation 1
PCSK2PCSK2proprotein convertase subtilisin/kexin type 2
MEG3MEG3maternally expressed 3 (non-protein coding)
YWHAZYWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide

Troyanskaya Laboratory - Princeton University