ASD

GO:0000245 spliceosome assembly (39)

GeneInput weightStandardRank
SRPK2--171
SCAF11--291
SRSF1--516
SFSWAP--680
RBM5--784
MBNL1--956
SRSF5--1085
SNRPE--1101
SRSF10--1221
CELF2--1303
DDX1--1332
SF3A2--1383
SRSF9--1459
PTBP2--1558
PSIP1--1794
SNRPG--1855
CELF4--2224
CELF1--2232
SF1--2557
SNRNP200--12747
PRPF6--2849
SRSF12--3143
DDX39B--3165
SF3A1--3851
CRNKL1--4816
SRSF6--7591
SNRPD2--8079
TXNL4A--14329
DDX23--15217
SLU7--15784
ZRSR2--20730
SNRPD1--22863
PRPF19--22991
SMN1--123959
USP39--24080
SMN2--124729
SF3A3--24887
GEMIN6--24931
GEMIN2--25309

Network

GO:0000245

Network
Enrichment
NameDescriptionExternal IDs
SRPK2SRSF protein kinase 2 Entrez:6733  HPRD: 04280  Ensembl: ENSG00000135250  HGNC: 11306 
SCAF11SR-related CTD-associated factor 11 Entrez:9169  HGNC: 10784  HPRD: 04720 
SRSF1serine/arginine-rich splicing factor 1 Entrez:6426  HGNC: 10780  HPRD: 02887 
SFSWAPsplicing factor, suppressor of white-apricot homolog (Drosophila) Entrez:6433  Ensembl: ENSG00000061936  HGNC: 10790  HPRD: 09055 
RBM5RNA binding motif protein 5 Entrez:10181  Ensembl: ENSG00000003756  HPRD: 06052  HGNC: 9902 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SRPK2SRSF protein kinase 2
SCAF11SR-related CTD-associated factor 11
SRSF1serine/arginine-rich splicing factor 1
SFSWAPsplicing factor, suppressor of white-apricot homolog (Drosophila)
RBM5RNA binding motif protein 5
Query geneGeneGene descriptionEdge score
SRPK2SRPK2SRSF protein kinase 2
SCAF11SCAF11SR-related CTD-associated factor 11
SRSF1SRSF1serine/arginine-rich splicing factor 1
SFSWAPSFSWAPsplicing factor, suppressor of white-apricot homolog (Drosophila)
RBM5RBM5RNA binding motif protein 5

Troyanskaya Laboratory - Princeton University