ASD

GO:0051279 regulation of release of sequestered calcium ion into cytosol (22)

GeneInput weightStandardRank
CALM3--352
SNCA--1667
DRD10.251899
RYR2--1959
CALM1--1029
THY1--1580
FKBP1B--2346
TRPC1--2648
CALM2--2814
CASQ1--2959
LHCGR0.2513057
EDNRA--13857
LACRT--7733
XCL1--7819
F2RL3--9626
LYN--10336
IL13--12888
MS4A2--13136
BDKRB1--18217
F2--118599
F2R--20036
TGFB10.25120135

Network

GO:0051279

Network
Enrichment
NameDescriptionExternal IDs
CALM3calmodulin 3 (phosphorylase kinase, delta) Entrez:808  HPRD: 00243  Ensembl: ENSG00000160014  HGNC: 1449 
SNCAsynuclein, alpha (non A4 component of amyloid precursor) Entrez:6622  HPRD: 01227  HGNC: 11138  Ensembl: ENSG00000145335 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
RYR2ryanodine receptor 2 (cardiac) Entrez:6262  Ensembl: ENSG00000198626  HGNC: 10484  HPRD: 01619 
CALM1calmodulin 1 (phosphorylase kinase, delta) Entrez:801  HPRD: 00241  HGNC: 1442  Ensembl: ENSG00000198668 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CALM3calmodulin 3 (phosphorylase kinase, delta)
SNCAsynuclein, alpha (non A4 component of amyloid precursor)
DRD1dopamine receptor D1
RYR2ryanodine receptor 2 (cardiac)
CALM1calmodulin 1 (phosphorylase kinase, delta)
Query geneGeneGene descriptionEdge score
CALM3CALM3calmodulin 3 (phosphorylase kinase, delta)
SNCASNCAsynuclein, alpha (non A4 component of amyloid precursor)
DRD1DRD1dopamine receptor D1
RYR2RYR2ryanodine receptor 2 (cardiac)
CALM1CALM1calmodulin 1 (phosphorylase kinase, delta)

Troyanskaya Laboratory - Princeton University