ASD

GO:0070120 ciliary neurotrophic factor-mediated signaling pathway (5)

GeneInput weightStandardRank
CNTFR--1675
LIFR--2506
IL6ST--3678
CNTF--5784
IL6R--19897

Network

GO:0070120

Network
Enrichment
NameDescriptionExternal IDs
CNTFRciliary neurotrophic factor receptor Entrez:1271  Ensembl: ENSG00000122756  HGNC: 2170  HPRD: 00348 
LIFRleukemia inhibitory factor receptor alpha Entrez:3977  HPRD: 01048  HGNC: 6597  Ensembl: ENSG00000113594 
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor) Entrez:3572  HGNC: 6021  Ensembl: ENSG00000134352  HPRD: 02824 
CNTFciliary neurotrophic factor Entrez:1270  Ensembl: ENSG00000242689  HGNC: 2169  HPRD: 00347 
IL6Rinterleukin 6 receptor Entrez:3570  HGNC: 6019  HPRD: 01000  Ensembl: ENSG00000160712 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CNTFRciliary neurotrophic factor receptor
LIFRleukemia inhibitory factor receptor alpha
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)
CNTFciliary neurotrophic factor
IL6Rinterleukin 6 receptor
Query geneGeneGene descriptionEdge score
CNTFRCNTFRciliary neurotrophic factor receptor
LIFRLIFRleukemia inhibitory factor receptor alpha
IL6STIL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)
CNTFCNTFciliary neurotrophic factor
IL6RIL6Rinterleukin 6 receptor

Troyanskaya Laboratory - Princeton University