ASD

GO:0001843 neural tube closure (46)

GeneInput weightStandardRank
LRP6--279
SFRP1--387
SALL1--506
PFN1--548
PAX2--653
LHX2--655
TSC10.251790
PTCH1--1972
LMO4--1244
DLC1--1282
ENAH--1348
ZIC2--11609
VANGL2--1793
COBL0.2512536
TULP3--2770
SKI--2904
TFAP2A--12923
DEAF11.013084
FZD3--3193
TGIF1--13264
OPA1--3271
T--3286
WNT5A--3319
ALX1--4544
RGMA--4758
SFRP2--5252
CELSR1--6180
IFT122--16355
ZEB2--6361
BMP4--16499
DVL2--6546
TWIST1--16980
VASP--7880
KDM2B--8359
TSC20.2519351
SUFU--19372
SALL4--9929
BBS4--110131
FUZ--12978
PTK7--13643
TEAD2--19466
FZD6--19921
ADM--21106
KAT2A--21262
BCL10--122368
LIAS--24813

Network

GO:0001843

Network
Enrichment
NameDescriptionExternal IDs
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
SALL1sal-like 1 (Drosophila) Entrez:6299  HGNC: 10524  Ensembl: ENSG00000103449  HPRD: 03742 
PFN1profilin 1 Entrez:5216  Ensembl: ENSG00000108518  HGNC: 8881  HPRD: 01452 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
LRP6low density lipoprotein receptor-related protein 6
SFRP1secreted frizzled-related protein 1
SALL1sal-like 1 (Drosophila)
PFN1profilin 1
PAX2paired box 2
Query geneGeneGene descriptionEdge score
LRP6LRP6low density lipoprotein receptor-related protein 6
SFRP1SFRP1secreted frizzled-related protein 1
SALL1SALL1sal-like 1 (Drosophila)
PFN1PFN1profilin 1
PAX2PAX2paired box 2

Troyanskaya Laboratory - Princeton University