ASD

GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity (133)

GeneInput weightStandardRank
KRAS--157
NEUROD2--98
NEUROD1--1127
NCOA3--192
CAMK2A--249
LRP6--279
EP300--1318
ERC1--494
HDAC4--696
UBE2N--734
TAB2--785
SMARCA4--801
EDA--1925
AKT10.2511020
NKX2-2--1120
RELA--1142
MAP3K7--1275
PTEN1.011389
MTDH--1461
PSMA6--1510
WNT10B--1517
UBE2I--1578
ZIC2--11609
ARHGEF2--1819
AR0.2511902
PPARGC1A--1909
HDAC5--1950
FOXA1--1990
EPHA5--2077
FZD4--12229
PPP2R5B--2296
TERF2IP--2298
WNT20.2512299
ARID5B--2503
MAP3K13--2864
NEUROG2--2989
WNT5A--3319
TP53BP1--3617
TAB3--3641
WNT1--4383
NEUROG10.2514644
CEBPG--4660
NKX6-1--4665
EDA2R--4972
TNFSF11--15271
TNFRSF11A--15293
NFKBIA--5569
JMY--5725
GTF2A2--5744
PLA2G1B--6059
TSSK4--6067
NGF0.2516229
TCF3--6420
DVL2--6546
TGFBR3--6672
UBC--6756
IL4--6852
TAB1--7218
ABRA--7831
IL10--19513
IL5--9669
TRIM320.2519794
NEUROG3--10352
SMO0.25110504
AMH--10601
PPAP2B--10628
IL1B--110818
RHEBL1--10910
UBE2V1--11027
TRAF6--11055
DDR2--12143
KDM1A--12183
IL6--112695
TLR4--112795
SMARCB1--112857
RNF31--12873
AGT--113305
TLR9--13360
MALT1--13522
IRAK3--14633
IRAK2--15024
TNFRSF8--15239
TNF0.25115243
NFKB2--15507
FZD2--16930
TRAF1--18373
SHH--118571
TLR2--119246
UBB--19448
TRAF5--19894
TGFB10.25120135
PRDX3--20199
IKBKB--20225
NFKB1--20281
JUP--120291
CDKN2A--120587
TIRAP--20658
FZD1--20775
RIPK2--20830
STK36--21217
NFAM1--21440
NOD2--121514
RNF25--21592
IRAK1--21640
ADAM8--21797
NPM1--121865
HMGN3--21870
TICAM1--21880
INS--122047
PYCARD--22145
BCL10--122368
TLR3--22478
DDX58--22544
RBCK1--22556
RIPK1--22681
PPARG--122729
NFKBIB--22875
AGER--22895
ANXA3--22980
MYD88--23106
MAVS--23348
NOD1--23388
IKBKG--123539
CARD11--23562
TRAF2--23686
ICAM1--23720
SPHK1--24069
SP100--24329
RPS27A--24381
UBA52--24384
CHUK--24756
CAT--25268
CLU--25437

Network

GO:0051091

Network
Enrichment
NameDescriptionExternal IDs
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
NEUROD2neuronal differentiation 2 Entrez:4761  HPRD: 03429  HGNC: 7763 
NEUROD1neuronal differentiation 1 Entrez:4760  HPRD: 03428  HGNC: 7762  Ensembl: ENSG00000162992 
NCOA3nuclear receptor coactivator 3 Entrez:8202  HGNC: 7670  Ensembl: ENSG00000124151  HPRD: 03570 
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha Entrez:815  HGNC: 1460  HPRD: 06532  Ensembl: ENSG00000070808 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KRASKirsten rat sarcoma viral oncogene homolog
NEUROD2neuronal differentiation 2
NEUROD1neuronal differentiation 1
NCOA3nuclear receptor coactivator 3
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha
Query geneGeneGene descriptionEdge score
KRASKRASKirsten rat sarcoma viral oncogene homolog
NEUROD2NEUROD2neuronal differentiation 2
NEUROD1NEUROD1neuronal differentiation 1
NCOA3NCOA3nuclear receptor coactivator 3
CAMK2ACAMK2Acalcium/calmodulin-dependent protein kinase II alpha

Troyanskaya Laboratory - Princeton University