ASD

GO:0048168 regulation of neuronal synaptic plasticity (43)

GeneInput weightStandardRank
CAMK2B0.25155
KRAS--157
GRIN2A0.25166
GRIK20.51232
GRM50.251240
CAMK2A--249
GRIN1--294
RASGRF1--335
NF10.251372
DBN1--385
GRIK1--481
SNCA--1667
CNTN2--674
KCNJ10--1733
GRIN2B1.01763
RIMS10.51777
DLG4--857
DRD10.251899
NCDN--950
BHLHE40--1054
DRD50.2511103
VGF0.2511782
UNC13A--1859
BCAN--1869
RAB11A--2051
PPFIA3--2061
NETO1--2632
EGR1--3062
SYP--3133
NPTN--3227
DRD20.2513749
SYNGR1--4153
S100B--4199
HRAS0.2515086
EGR20.2516247
ARC0.2518587
SHISA9--12388
PMCH--12542
AGT--113305
UNC13B--13412
MYLK2--113626
NRAS--114119
APOE0.25123516

Network

GO:0048168

Network
Enrichment
NameDescriptionExternal IDs
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta Entrez:816  Ensembl: ENSG00000058404  HGNC: 1461  HPRD: 12127 
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
GRM5glutamate receptor, metabotropic 5 Entrez:2915  HGNC: 4597  Ensembl: ENSG00000168959 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta
KRASKirsten rat sarcoma viral oncogene homolog
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIK2glutamate receptor, ionotropic, kainate 2
GRM5glutamate receptor, metabotropic 5
Query geneGeneGene descriptionEdge score
CAMK2BCAMK2Bcalcium/calmodulin-dependent protein kinase II beta
KRASKRASKirsten rat sarcoma viral oncogene homolog
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
GRM5GRM5glutamate receptor, metabotropic 5

Troyanskaya Laboratory - Princeton University