ASD

GO:0042770 signal transduction in response to DNA damage (111)

GeneInput weightStandardRank
PSMA1--58
PSMD14--104
PSMA4--166
PSMB3--234
SOX4--250
PSMA5--284
EP300--1318
PSMD8--371
PSMA3--460
PSMB1--501
PPP2R5C--555
PSMC6--679
PSMD6--688
PSMB7--745
PSME4--787
PSMC2--815
TOPORS--1894
PSMD11--967
HIPK2--1051
FOXO3--1056
PSMB4--1091
CDKN1B--1162
PSMD1--1168
PSMA7--1174
DYRK2--1203
PSMC4--1269
PSMC1--1296
BAG6--1305
PSMA6--1510
PSMD12--1573
PSMB6--1607
PSMD2--1706
PSMC5--1897
PSMD3--2008
PSMD4--2087
PSMC3--2240
ABL1--2404
PSMD10--2412
PSMD7--2481
PSMA2--2699
PAXIP1--2915
GRB2--2962
FNIP2--3028
PSMD13--3051
MSH6--13445
USP10--3561
ATM--13622
MAPK14--3975
GML--4230
WNT1--4383
KAT5--4618
GADD45A--5185
XPA--15296
CIDEA--6211
MSH2--16311
TFAP4--6377
MYO6--16390
PCBP4--6634
MDM2--6675
UBC--6756
CDIP1--7580
CDKN1A--7714
BCL3--7998
RFWD2--10076
PSMA8--10087
MBD40.25110712
RBM38--11401
PSMB2--11986
PSMB11--12480
UACA--12955
MAD2L2--13802
PSMD9--13911
PSME2--14327
USP28--15068
NBN--116066
TP530.25118277
TP73--18810
UBB--19448
PSMD5--19823
SMC1A--19955
BBC3--20534
PSME1--21072
ING4--21206
PSMB9--21373
PSMB10--21853
AEN--22019
PSMB8--22146
PSME3--22162
PSMF1--22424
TP63--122528
CEP63--22973
HMOX1--23938
GTSE1--24085
CIDEB--24163
SP100--24329
IFI16--24354
RPS27A--24381
UBA52--24384
TRIAP1--24476
BRCA1--124573
IKBKE--24643
PGAP2--24686
CHEK2--124807
PHLDA3--24856
RPS27L--25183
PSMB5--25250
PML--25277
CDK2--25445
SFN--25459
MLH1--125513
AIFM1--25591

Network

GO:0042770

Network
Enrichment
NameDescriptionExternal IDs
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4 Entrez:5685  Ensembl: ENSG00000041357  HPRD: 10168  HGNC: 9533 
PSMB3proteasome (prosome, macropain) subunit, beta type, 3 Entrez:5691  HPRD: 03709  Ensembl: ENSG00000108294  HGNC: 9540 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMB3proteasome (prosome, macropain) subunit, beta type, 3
SOX4SRY (sex determining region Y)-box 4
Query geneGeneGene descriptionEdge score
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMA4PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMB3PSMB3proteasome (prosome, macropain) subunit, beta type, 3
SOX4SOX4SRY (sex determining region Y)-box 4

Troyanskaya Laboratory - Princeton University