ASD

GO:0060828 regulation of canonical Wnt receptor signaling pathway (99)

GeneInput weightStandardRank
UBR5--193
SOX2--1200
USP34--231
FGFR2--1237
SOX4--250
FGF9--262
APC0.251266
LRP6--279
SFRP1--387
CDK140.251536
CSNK1D--699
CSNK1E0.251752
SMAD3--823
EDA--1925
SOX9--1970
APC2--1115
AES--1230
TNKS--1414
HDAC2--1440
LEF1--1499
LRP4--1500
WNT10B--1517
WNT2B--1673
MCC--2167
STK4--2276
WNT20.2512299
DKK2--2331
FGFR3--12640
DLX5--2706
LATS1--2781
CTNND1--2948
EGR1--3062
WNT5A--3319
DAB2IP--3482
TCF7L20.513548
SIAH2--3729
DIXDC1--3734
SOX17--4024
AXIN2--14260
CAPRIN2--4284
TNKS2--4385
AXIN1--14419
FGF10--14532
CYLD--14624
RSPO2--4631
DRAXIN--4717
WNT3A--4747
ZNF703--5031
SFRP2--5252
DKK3--5413
PRICKLE1--15552
SOX7--6117
GLI1--6241
GLI3--16261
TLE2--6532
SOST--6885
SCYL2--7130
RSPO1--7229
ILK--7305
SFRP4--7310
WNT7A--7312
WNT11--7820
RNF146--7910
FRZB--8105
GPC3--18430
NKX2-50.2518486
BAMBI--8550
TBX18--8991
LRP5--19420
LATS2--9736
CCNY--10662
KREMEN1--10806
SFRP5--11273
DKK1--11567
NPHP3--113474
MESP1--13805
NRARP--14597
INVS--114708
DDIT3--14883
WNT5B--15534
WLS--15707
SHH--118571
POU5F1--19704
FZD6--19921
EMD--120034
NFKB1--20281
JUP--120291
FZD1--20775
TRPM4--20948
STK3--21167
WNT4--21809
YAP1--22469
PFDN5--23272
CBY1--23816
SNAI2--123962
COL1A1--124140
WWTR1--24317
DAB2--25338
CAV1--125381

Network

GO:0060828

Network
Enrichment
NameDescriptionExternal IDs
UBR5ubiquitin protein ligase E3 component n-recognin 5 Entrez:51366  HPRD: 06436  Ensembl: ENSG00000104517  HGNC: 16806 
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
USP34ubiquitin specific peptidase 34 Entrez:9736  HGNC: 20066  HPRD: 11665  Ensembl: ENSG00000115464 
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
SOX4SRY (sex determining region Y)-box 4 Entrez:6659  HPRD: 01695  HGNC: 11200  Ensembl: ENSG00000124766 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
UBR5ubiquitin protein ligase E3 component n-recognin 5
SOX2SRY (sex determining region Y)-box 2
USP34ubiquitin specific peptidase 34
FGFR2fibroblast growth factor receptor 2
SOX4SRY (sex determining region Y)-box 4
Query geneGeneGene descriptionEdge score
UBR5UBR5ubiquitin protein ligase E3 component n-recognin 5
SOX2SOX2SRY (sex determining region Y)-box 2
USP34USP34ubiquitin specific peptidase 34
FGFR2FGFR2fibroblast growth factor receptor 2
SOX4SOX4SRY (sex determining region Y)-box 4

Troyanskaya Laboratory - Princeton University