ASD

GO:0007257 activation of JUN kinase activity (31)

GeneInput weightStandardRank
MAP3K9--462
SPAG9--558
GAB1--1198
MAP3K5--1220
PKN1--1967
MAPK8IP3--2274
MAP4K5--2894
MAP3K10--2968
MAP3K2--3184
WNT5A--3319
MAP3K1--13381
DAB2IP--3482
AXIN1--14419
MAP2K7--5837
WNT7B--7113
WNT7A--7312
FGD4--17457
DAXX--8508
MAP3K11--12938
MDFI--13519
CCL19--14578
BIRC7--19826
PTPLAD1--20272
MAP4K2--20522
MDFIC--21692
MAP4K1--22336
DBNL--22402
RIPK1--22681
MUL1--22953
SYK--23906
MAP3K6--24220

Network

GO:0007257

Network
Enrichment
NameDescriptionExternal IDs
MAP3K9mitogen-activated protein kinase kinase kinase 9 Entrez:4293  Ensembl: ENSG00000006432  HGNC: 6861  HPRD: 15965 
SPAG9sperm associated antigen 9 Entrez:9043  HPRD: 10398  HGNC: 14524  Ensembl: ENSG00000008294 
GAB1GRB2-associated binding protein 1 Entrez:2549  HPRD: 05116  Ensembl: ENSG00000109458  HGNC: 4066 
MAP3K5mitogen-activated protein kinase kinase kinase 5 Entrez:4217  HPRD: 03904  HGNC: 6857  Ensembl: ENSG00000197442 
PKN1protein kinase N1 Entrez:5585  HPRD: 03019  Ensembl: ENSG00000123143  HGNC: 9405 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAP3K9mitogen-activated protein kinase kinase kinase 9
SPAG9sperm associated antigen 9
GAB1GRB2-associated binding protein 1
MAP3K5mitogen-activated protein kinase kinase kinase 5
PKN1protein kinase N1
Query geneGeneGene descriptionEdge score
MAP3K9MAP3K9mitogen-activated protein kinase kinase kinase 9
SPAG9SPAG9sperm associated antigen 9
GAB1GAB1GRB2-associated binding protein 1
MAP3K5MAP3K5mitogen-activated protein kinase kinase kinase 5
PKN1PKN1protein kinase N1

Troyanskaya Laboratory - Princeton University