Gene | Input weight | Standard | Rank | |
TOP1 | - | - | 308 | |
TOP2B | - | - | 615 | |
HMGB1 | 0.25 | 1 | 2379 | |
HMGB2 | - | - | 3362 | |
ERCC3 | - | -1 | 7110 | |
TOP3B | - | - | 10706 | |
TOP1MT | - | - | 22926 | |
TOP3A | - | - | 23752 | |
TOP2A | - | - | 24765 |
GO:0006265
Name | Description | External IDs |
TOP1 | topoisomerase (DNA) I | Entrez:7150  Ensembl: ENSG00000198900  HGNC: 11986  HPRD: 00535  |
TOP2B | topoisomerase (DNA) II beta 180kDa | Entrez:7155  HGNC: 11990  Ensembl: ENSG00000077097  HPRD: 00537  |
HMGB1 | high mobility group box 1 | Entrez:3146  HGNC: 4983  HPRD: 01228  Ensembl: ENSG00000189403  |
HMGB2 | high mobility group box 2 | Entrez:3148  HGNC: 5000  HPRD: 01229  |
ERCC3 | excision repair cross-complementing rodent repair deficiency, complementation group 3 | Entrez:2071  Ensembl: ENSG00000163161  HGNC: 3435  HPRD: 00593  |
Geneset | Type | Freq. (Network vs Genome) | P-Value (FDR Corrected) | Genes |
Gene | Description | Avg. edge score to query | Rank | In geneset | In query |
TOP1 | topoisomerase (DNA) I | ||||
TOP2B | topoisomerase (DNA) II beta 180kDa | ||||
HMGB1 | high mobility group box 1 | ||||
HMGB2 | high mobility group box 2 | ||||
ERCC3 | excision repair cross-complementing rodent repair deficiency, complementation group 3 |
Query gene | Gene | Gene description | Edge score |
TOP1 | TOP1 | topoisomerase (DNA) I | |
TOP2B | TOP2B | topoisomerase (DNA) II beta 180kDa | |
HMGB1 | HMGB1 | high mobility group box 1 | |
HMGB2 | HMGB2 | high mobility group box 2 | |
ERCC3 | ERCC3 | excision repair cross-complementing rodent repair deficiency, complementation group 3 |