ASD

GO:0051345 positive regulation of hydrolase activity (386)

GeneInput weightStandardRank
GNAO1--4
GNB1--24
PLCB1--148
CREB1--100
PSMD14--104
HTR2A0.251121
RGS70.251135
ABR--160
AMPH--169
ADCY2--175
RGS4--178
GNAQ--189
PRKCE--204
RABGAP1--212
DNAJB6--222
GRM50.251240
RASGRF1--335
CALM3--352
AKAP6--364
NF10.251372
SFRP1--387
GSK3B--427
ARHGAP5--464
ADCY10.251466
JUN--511
RAPGEF2--540
PRKACB--584
CRHR1--589
ITPR1--1597
ADRM1--611
SNCA--1667
SIPA1L1--716
HSPE1--778
TSC10.251790
CCKBR--794
RGS6--805
SOS1--1810
SMAD3--823
RABGAP1L--846
RGS11--884
DRD10.251899
MAP2K10.251907
ARHGAP35--908
CAMK4--916
NTSR2--920
CALCA--1013
PRKCA--1027
CALM1--1029
NDEL10.2511074
DRD50.2511103
MAPK8--1214
MAP3K5--1220
PRKAR1B--1257
ADCYAP1R1--1273
DLC1--1282
BAD--1290
COL4A3--11327
ADRA2A0.2511399
RALGAPA1--1420
PRKCG--11483
RAP1GAP--1556
THY1--1580
PTGER3--1587
RGS17--1702
DOCK40.2511765
GNG13--1774
HIP1--1797
BCR--11839
ADCY9--1850
ADRA1A--1858
HCRTR20.2511860
PDE1C--1867
RASAL2--1889
CCK0.2511899
TBC1D10B--1952
AGTR20.2511955
PDE1A--1968
RASA1--1983
NMBR--2016
EDNRB--12042
ELMOD1--2135
ROBO1--2182
PRKAR2B--2211
GNA11--2281
MTCH1--2317
RAP1GDS1--2341
CHN2--2347
HMGB10.2512379
PRKAR1A--12428
PDE1B--2534
EGFR--12546
PPP2R4--2609
PCNA--2671
DOCK1--2675
PREX1--2760
ADCY8--2785
RGS5--2795
CHRM2--2799
CALM2--2814
ADCY6--2877
VAV3--2908
FZD10--2957
LHCGR0.2513057
PTK2B--3063
ALDOB--3137
PREX2--3163
ARHGAP1--3304
HMGB2--3362
HOMER10.2513402
MSH6--13445
DAB2IP--3482
CDKL5--13600
AHSA1--3607
RASAL1--3614
GNA14--3634
ARHGAP26--13662
DRD20.2513749
AVPR1A0.513803
EDNRA--13857
RGS12--3946
SYNGAP11.014039
PRKACG--4112
LPAR1--4170
AXIN2--14260
RGS20--4292
ADCY5--4295
S1PR1--4301
P2RY1--4342
AXIN1--14419
MOAP1--4508
FGF10--14532
ARHGAP29--4559
RGS16--4657
SENP1--4701
PLCG1--4744
WNT3A--4747
ARAP3--4767
RALGAPA2--4803
TERF1--4825
BMP2--14855
RASA2--4877
HSPD1--14908
MEN1--14917
NLRP30.2514959
MYO9B0.515005
RGS2--5095
RGS8--5148
APAF10.2515149
IFNB1--5250
RANGAP1--5328
RGS9--5332
GPIHBP1--5357
NPR3--5370
ARHGAP6--5374
FASLG--15523
TBCD--5702
ADCY3--5755
SNX18--5776
FOXQ1--5820
SIVA1--5973
ADRBK1--6028
PLA2G1B--6059
SOX7--6117
NR1H2--6183
BIN1--6197
NGF0.2516229
AGTR1--16275
RHOG--6279
MSH2--16311
ALS2--16326
NMUR2--6430
LPAR2--6450
RGS22--6455
PRKCD--6504
CASP8AP2--6582
OPHN10.516584
RALBP1--6643
ERRFI1--6649
GNA13--6683
CASP30.2516694
TNNT2--16745
TNFSF15--6782
CHRM1--6796
RGS13--6883
PLCE1--6929
HTR2B--6992
RXFP3--6996
FRS2--7173
CASR--7200
NLRC4--7212
P2RY4--7298
PMAIP1--7385
GRHL3--7409
VCP--7434
HRH1--7471
FOXL2--17521
SYDE2--7604
FOXJ1--7628
MYBPC3--17697
WNT11--7820
PIN1--7940
ITPR2--8066
CXCL13--8148
MC3R0.2518188
GPR139--8207
RASGRP3--8406
RASGRP4--8409
NTRK10.2518522
AVPR1B0.2518546
C6--8602
C9--8637
GPR55--8693
LRRK2--18802
DAP--8832
RASA4--8961
AIFM3--8980
ADCY4--9091
CYCS--9251
RGN--9311
RGS18--9348
TSC20.2519351
RAB3GAP1--9492
EDN1--9540
BOK--9611
CCL11--9615
SSBP1--9617
F2RL3--9626
PRKACA--9630
SYDE1--9690
REST--9779
BAX--9833
ERN1--9939
FABP1--10047
TBC1D15--10227
RAB3GAP2--10501
RGS1--10535
F3--10889
SNX9--11169
PRKAR2A--11450
APOH--11562
TACR1--11618
HCRT0.25111633
RHOC--11655
CCKAR--11747
LPAR3--11897
ARHGAP8--11916
BCL2L10--12129
IQGAP1--12240
PDCD6--12294
SLC11A2--112770
IFNG--112827
UACA--12955
RGS14--12999
LMF1--13134
MS4A2--13136
FGF2--13150
AGT--113305
TNFRSF10B--13570
APOC2--13818
APOA5--113831
RGS21--13909
ARHGEF19--14560
CCL19--14578
SELE--14642
ALOX12--14851
FNTA--14922
TNF0.25115243
PPARGC1B--115356
CXCR2--15438
TAX1BP3--15553
RASA3--15787
MSH3--15835
SNX13--15948
ARHGEF10L--17881
TP530.25118277
CASP12--18416
F2--118599
APOA1--118958
NMUR1--19043
HSPA5--19143
ARHGEF6--19241
P2RX1--19303
EPHA2--119467
ALDH1A1--19488
CDC42EP2--19500
JAK2--119561
DOCK7--19597
RASAL3--19660
NLRP12--19807
ARRB1--19906
LTB4R--19987
GNAT1--119999
F2R--20036
VRK3--20233
PTPLAD1--20272
BNIP2--20381
EIF2AK3--20456
MYL3--120524
NLRP1--20532
BBC3--20534
RGS19--20558
CDKN2A--120587
IFT57--20635
P2RY11--20669
GNA15--20926
CASP90.25121044
ARHGAP15--21045
ARHGEF16--21200
SIPA1--21260
ARHGAP4--21362
C5AR1--21363
GABARAPL2--21370
ELMOD2--21506
ABHD5--121568
ITPR3--21697
TNFRSF10A--21740
NLRP2--21787
CCL21--21829
CCL24--21868
SLC9A3R1--21898
RALGAPB--22093
S1PR4--22105
RP2--122116
PYCARD--22145
PSME3--22162
GMIP--22274
APOA4--22292
CCR7--22367
PLCB2--22475
ARHGAP9--22481
TPD52L1--22519
GPR65--22555
CARD8--22573
CYR61--22574
RIPK1--22681
PPARG--122729
CCL26--22814
ADAP2--22843
MUL1--22953
CCL5--23042
P2RY6--23098
TGM2--23204
FADD--23261
PCOLCE2--23280
GNB2L1--23282
RGS3--23349
NOD1--23388
DIABLO--23456
CTGF--23607
SCRIB--23676
TRAF2--23686
TBC1D2--23738
NCKAP1L--23771
IFI27--23825
ARHGAP27--23975
P2RY2--24088
PLEK--24240
TPM1--124247
BCL2L13--24304
CLPX--24371
PCOLCE--24405
DNAJC1--24415
POT1--24483
CASP8--124587
RGS10--24612
FAS--124697
WRN--124741
LCK--24753
ANG--124879
ARAP1--24899
RACGAP1--24932
NR1H3--25006
CASP7--25028
STAT1--25107
RPS27L--25183
TNFSF10--25200
TRADD--25265
PML--25277
CAV1--125381
ADCY7--25408
CASP1--25470
RPS3--25585
AIFM1--25591
DNAJA3--25610
MYL4--25690
DNAJC10--25717

Network

GO:0051345

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1 Entrez:2782  HGNC: 4396  HPRD: 00766  Ensembl: ENSG00000078369 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
CREB1cAMP responsive element binding protein 1 Entrez:1385  HGNC: 2345  HPRD: 00442  Ensembl: ENSG00000118260 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CREB1cAMP responsive element binding protein 1
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNB1GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
CREB1CREB1cAMP responsive element binding protein 1
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14

Troyanskaya Laboratory - Princeton University