ASD

GO:0050810 regulation of steroid biosynthetic process (41)

GeneInput weightStandardRank
IGF1R--252
NR3C1--496
PROX1--997
FGF1--1892
INSIG1--2529
SF1--2557
SCAP--2683
SOD1--12702
LHCGR0.2513057
CYP17A10.2513984
TSPO0.2514009
BMP6--4358
IL1A--4651
POR0.2515184
DKK3--5413
ATP1A10.2515927
NR5A1--17328
CYP7A10.2517401
HRH1--7471
DHH--17475
STAR--8811
SNAI1--9198
REST--9779
INSIG2--10252
GFI1--111098
LEP0.25111864
FGF19--12130
IFNG--112827
TNF0.25115243
SREBF1--19464
ADORA2B--19522
SEC14L2--20125
NFKB1--20281
ABCG1--21175
WNT4--21809
IGF20.25122401
DHCR70.25122909
PRKAA1--22917
APOE0.25123516
SNAI2--123962
PEX2--125198

Network

GO:0050810

Network
Enrichment
NameDescriptionExternal IDs
IGF1Rinsulin-like growth factor 1 receptor Entrez:3480  Ensembl: ENSG00000140443  HPRD: 00932  HGNC: 5465 
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
PROX1prospero homeobox 1 Entrez:5629  HPRD: 03330  HGNC: 9459  Ensembl: ENSG00000117707 
FGF1fibroblast growth factor 1 (acidic) Entrez:2246  HGNC: 3665  Ensembl: ENSG00000113578  HPRD: 00567 
INSIG1insulin induced gene 1 Entrez:3638  HPRD: 03633  HGNC: 6083  Ensembl: ENSG00000186480 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
IGF1Rinsulin-like growth factor 1 receptor
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PROX1prospero homeobox 1
FGF1fibroblast growth factor 1 (acidic)
INSIG1insulin induced gene 1
Query geneGeneGene descriptionEdge score
IGF1RIGF1Rinsulin-like growth factor 1 receptor
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PROX1PROX1prospero homeobox 1
FGF1FGF1fibroblast growth factor 1 (acidic)
INSIG1INSIG1insulin induced gene 1

Troyanskaya Laboratory - Princeton University