ASD

GO:0032855 positive regulation of Rac GTPase activity (21)

GeneInput weightStandardRank
RASGRF1--335
SFRP1--387
GSK3B--427
DOCK40.2511765
FZD10--2957
PTK2B--3063
PREX2--3163
CDKL5--13600
RHOG--6279
ALS2--16326
RALBP1--6643
CCL11--9615
EPHA2--119467
DOCK7--19597
ARHGAP15--21045
ARHGEF16--21200
CCL24--21868
CCL26--22814
SCRIB--23676
NCKAP1L--23771
ARHGAP27--23975

Network

GO:0032855

Network
Enrichment
NameDescriptionExternal IDs
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1 Entrez:5923  HGNC: 9875  Ensembl: ENSG00000058335 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
GSK3Bglycogen synthase kinase 3 beta Entrez:2932  Ensembl: ENSG00000082701  HPRD: 05418  HGNC: 4617 
DOCK4dedicator of cytokinesis 4 Entrez:9732  HGNC: 19192  HPRD: 07407  Ensembl: ENSG00000128512 
FZD10frizzled family receptor 10 Entrez:11211  HGNC: 4039  HPRD: 05853  Ensembl: ENSG00000111432 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
SFRP1secreted frizzled-related protein 1
GSK3Bglycogen synthase kinase 3 beta
DOCK4dedicator of cytokinesis 4
FZD10frizzled family receptor 10
Query geneGeneGene descriptionEdge score
RASGRF1RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
SFRP1SFRP1secreted frizzled-related protein 1
GSK3BGSK3Bglycogen synthase kinase 3 beta
DOCK4DOCK4dedicator of cytokinesis 4
FZD10FZD10frizzled family receptor 10

Troyanskaya Laboratory - Princeton University