ASD

GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (119)

GeneInput weightStandardRank
SOX11--96
TRIM33--1147
BMPR2--1281
SFRP1--387
NREP--417
NR3C1--496
ACVR1B--510
PEG10--627
SMAD4--821
SMAD3--823
SMURF2--889
CHRD--941
ACVR2A--965
PCSK6--1035
HIPK2--1051
BMP7--1137
BMPR1A--1140
SMAD7--1192
FKBP1A--1284
ACVR2B--11676
ONECUT2--1700
STRAP--1732
LEMD3--12084
FBN2--2131
GDF6--12291
SMAD6--2305
CITED2--2650
SMAD2--2694
BCL9L--2729
NOTCH1--12865
SKIL--2889
SKI--2904
CDKN1C--12938
SOSTDC1--3003
SMURF1--3060
CITED1--3064
WNT5A--3319
BMPER--3497
ITGA8--3626
GREM1--3867
HOXA13--4036
NKX2-1--4142
GLG1--4233
PRDM16--4345
BMP6--4358
WNT1--4383
FGF10--14532
FURIN--4605
RGMA--4758
BMP2--14855
MEN1--14917
HES5--4919
ZNF703--5031
BMP10--5102
SFRP2--5252
ADAM17--5323
NOG--15439
HES10.2515912
STK11--16000
ACVR1--16054
ADAMTSL2--6151
FOXD2--6176
NPNT--6188
CIDEA--6211
BMP4--16499
TGFBR3--6672
GDF7--6682
SOST--6885
CER1--6956
TGFBR1--17268
ILK--7305
FOXD4L1--7836
FOXD1--7884
PIN1--7940
GPC3--18430
BAMBI--8550
VWC2--8879
CHST11--9003
FOXD4L4--9599
GIPC1--9877
GATA6--110828
FBN1--110976
DKK1--11567
FOXD4--11635
ACVRL1--111656
ASPN--11718
FBXL15--12126
GATA4--112466
IL17F--12626
DAND5--12647
SKOR2--12780
SKOR1--12870
TGFB3--113097
FOXD4L5--13951
GDF2--14603
FST--14783
CDKN2B--14806
RBPMS--14967
FOXD4L2--16505
INHBA--16974
HSPA5--19143
FOXD4L6--19555
POU5F1--19704
TGFB10.25120135
FZD1--20775
EID2--21599
ING2--21967
CYR61--22574
SNX6--22713
TGFB1I1--23709
WWTR1--24317
THBS1--24444
LTBP1--24489
ENG--124746
TWSG1--24840
LTBP4--25003
FSTL3--25154
CAV1--125381
TTK--25648

Network

GO:0090092

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
TRIM33tripartite motif containing 33 Entrez:51592  HPRD: 10423  HGNC: 16290  Ensembl: ENSG00000197323 
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
NREPneuronal regeneration related protein Entrez:9315  HGNC: 16834  HPRD: 09545  Ensembl: ENSG00000134986 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
TRIM33tripartite motif containing 33
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
SFRP1secreted frizzled-related protein 1
NREPneuronal regeneration related protein
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
TRIM33TRIM33tripartite motif containing 33
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
SFRP1SFRP1secreted frizzled-related protein 1
NREPNREPneuronal regeneration related protein

Troyanskaya Laboratory - Princeton University