ASD

GO:0042430 indole-containing compound metabolic process (24)

GeneInput weightStandardRank
ATP2B20.513
GRIN2A0.25166
ASMTL--2405
ATP7A--12483
PDE1B--2534
CCBL1--2621
CYP19A10.2513823
SRD5A10.2514966
AANAT0.2515448
TPH20.2515693
ACMSD--5793
DDC0.2515929
TPH10.2516460
IDO2--7768
ASMT0.25110532
TDO20.25110565
KMO--13147
AFMID--14135
MAOA0.25119009
HAAO--19341
AADAT--19369
KYNU--22720
IDO1--23074
CCBL2--23177

Network

GO:0042430

Network
Enrichment
NameDescriptionExternal IDs
ATP2B2ATPase, Ca++ transporting, plasma membrane 2 Entrez:491  HGNC: 815  Ensembl: ENSG00000157087  HPRD: 00160 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
ASMTLacetylserotonin O-methyltransferase-like Entrez:8623  HGNC: 751  Ensembl: ENSG00000169093  HPRD: 02156 
ATP7AATPase, Cu++ transporting, alpha polypeptide Entrez:538  Ensembl: ENSG00000165240  HGNC: 869  HPRD: 02054 
PDE1Bphosphodiesterase 1B, calmodulin-dependent Entrez:5153  HGNC: 8775  Ensembl: ENSG00000123360  HPRD: 01388 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ATP2B2ATPase, Ca++ transporting, plasma membrane 2
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
ASMTLacetylserotonin O-methyltransferase-like
ATP7AATPase, Cu++ transporting, alpha polypeptide
PDE1Bphosphodiesterase 1B, calmodulin-dependent
Query geneGeneGene descriptionEdge score
ATP2B2ATP2B2ATPase, Ca++ transporting, plasma membrane 2
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
ASMTLASMTLacetylserotonin O-methyltransferase-like
ATP7AATP7AATPase, Cu++ transporting, alpha polypeptide
PDE1BPDE1Bphosphodiesterase 1B, calmodulin-dependent

Troyanskaya Laboratory - Princeton University