ASD

GO:0006198 cAMP catabolic process (9)

GeneInput weightStandardRank
PDE4D--348
PDE4A--1260
PDE2A--1938
PDE4B--2178
PDE1B--2534
PDE11A--2780
PDE4C--3021
PDE3A--3628
PDE3B--3819

Network

GO:0006198

Network
Enrichment
NameDescriptionExternal IDs
PDE4Dphosphodiesterase 4D, cAMP-specific Entrez:5144  HPRD: 02530  HGNC: 8783  Ensembl: ENSG00000113448 
PDE4Aphosphodiesterase 4A, cAMP-specific Entrez:5141  HPRD: 02527  HGNC: 8780  Ensembl: ENSG00000065989 
PDE2Aphosphodiesterase 2A, cGMP-stimulated Entrez:5138  HGNC: 8777  Ensembl: ENSG00000186642  HPRD: 04041 
PDE4Bphosphodiesterase 4B, cAMP-specific Entrez:5142  HPRD: 02528  Ensembl: ENSG00000184588  HGNC: 8781 
PDE1Bphosphodiesterase 1B, calmodulin-dependent Entrez:5153  HGNC: 8775  Ensembl: ENSG00000123360  HPRD: 01388 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PDE4Dphosphodiesterase 4D, cAMP-specific
PDE4Aphosphodiesterase 4A, cAMP-specific
PDE2Aphosphodiesterase 2A, cGMP-stimulated
PDE4Bphosphodiesterase 4B, cAMP-specific
PDE1Bphosphodiesterase 1B, calmodulin-dependent
Query geneGeneGene descriptionEdge score
PDE4DPDE4Dphosphodiesterase 4D, cAMP-specific
PDE4APDE4Aphosphodiesterase 4A, cAMP-specific
PDE2APDE2Aphosphodiesterase 2A, cGMP-stimulated
PDE4BPDE4Bphosphodiesterase 4B, cAMP-specific
PDE1BPDE1Bphosphodiesterase 1B, calmodulin-dependent

Troyanskaya Laboratory - Princeton University