ASD

GO:0007212 dopamine receptor signaling pathway (17)

GeneInput weightStandardRank
GNAO1--4
GNAQ--189
DRD10.251899
DRD50.2511103
GNAL--1177
GNAS--11842
GNA11--2281
CALY--2456
GNA14--3634
DRD20.2513749
FLNA--14285
ADCY5--4295
DRD30.2514349
RGS9--5332
DRD40.2517021
GNA15--20926
SLC9A3R1--21898

Network

GO:0007212

Network
Enrichment
NameDescriptionExternal IDs
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O Entrez:2775  HPRD: 00757  HGNC: 4389  Ensembl: ENSG00000087258 
GNAQguanine nucleotide binding protein (G protein), q polypeptide Entrez:2776  HGNC: 4390  HPRD: 02998 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
DRD5dopamine receptor D5 Entrez:1816  HGNC: 3026  Ensembl: ENSG00000169676  HPRD: 00542 
GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type Entrez:2774  HGNC: 4388  Ensembl: ENSG00000141404  HPRD: 00758 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQguanine nucleotide binding protein (G protein), q polypeptide
DRD1dopamine receptor D1
DRD5dopamine receptor D5
GNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
Query geneGeneGene descriptionEdge score
GNAO1GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQGNAQguanine nucleotide binding protein (G protein), q polypeptide
DRD1DRD1dopamine receptor D1
DRD5DRD5dopamine receptor D5
GNALGNALguanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type

Troyanskaya Laboratory - Princeton University