ASD

GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway (17)

GeneInput weightStandardRank
SMAD4--821
HIPK2--1051
CITED2--2650
CDKN1C--12938
CITED1--3064
ITGA8--3626
FURIN--4605
MEN1--14917
ADAM17--5323
STK11--16000
NPNT--6188
TGFBR3--6672
GIPC1--9877
CDKN2B--14806
ING2--21967
TGFB1I1--23709
THBS1--24444

Network

GO:0030511

Network
Enrichment
NameDescriptionExternal IDs
SMAD4SMAD family member 4 Entrez:4089  Ensembl: ENSG00000141646  HGNC: 6770  HPRD: 02995 
HIPK2homeodomain interacting protein kinase 2 Entrez:28996  HPRD: 06039  HGNC: 14402  Ensembl: ENSG00000064393 
CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 Entrez:10370  HGNC: 1987  HPRD: 04245  Ensembl: ENSG00000164442 
CDKN1Ccyclin-dependent kinase inhibitor 1C (p57, Kip2) Entrez:1028  HPRD: 02913  HGNC: 1786  Ensembl: ENSG00000129757 
CITED1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 Entrez:4435  HGNC: 1986  HPRD: 02146  Ensembl: ENSG00000125931 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SMAD4SMAD family member 4
HIPK2homeodomain interacting protein kinase 2
CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CDKN1Ccyclin-dependent kinase inhibitor 1C (p57, Kip2)
CITED1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
Query geneGeneGene descriptionEdge score
SMAD4SMAD4SMAD family member 4
HIPK2HIPK2homeodomain interacting protein kinase 2
CITED2CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CDKN1CCDKN1Ccyclin-dependent kinase inhibitor 1C (p57, Kip2)
CITED1CITED1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

Troyanskaya Laboratory - Princeton University