ASD

GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation (18)

GeneInput weightStandardRank
BMPR2--1281
ACVR1B--510
SMAD4--821
BMP7--1137
BMPR1A--1140
GDF6--12291
BMP6--4358
BMP2--14855
BMP10--5102
BMP4--16499
GDF7--6682
TGFBR1--17268
TGFB3--113097
GDF2--14603
RBPMS--14967
TGFB10.25120135
ENG--124746
TTK--25648

Network

GO:0010862

Network
Enrichment
NameDescriptionExternal IDs
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
ACVR1Bactivin A receptor, type IB Entrez:91  Ensembl: ENSG00000135503  HGNC: 172  HPRD: 03193 
SMAD4SMAD family member 4 Entrez:4089  Ensembl: ENSG00000141646  HGNC: 6770  HPRD: 02995 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
BMPR1Abone morphogenetic protein receptor, type IA Entrez:657  HGNC: 1076  Ensembl: ENSG00000107779  HPRD: 03192 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
ACVR1Bactivin A receptor, type IB
SMAD4SMAD family member 4
BMP7bone morphogenetic protein 7
BMPR1Abone morphogenetic protein receptor, type IA
Query geneGeneGene descriptionEdge score
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
ACVR1BACVR1Bactivin A receptor, type IB
SMAD4SMAD4SMAD family member 4
BMP7BMP7bone morphogenetic protein 7
BMPR1ABMPR1Abone morphogenetic protein receptor, type IA

Troyanskaya Laboratory - Princeton University