ASD

GO:0002666 positive regulation of T cell tolerance induction (6)

GeneInput weightStandardRank
CBLB--1161
ITCH--2932
CD3E--9680
TGFBR2--110407
FOXP3--112457
IDO1--23074

Network

GO:0002666

Network
Enrichment
NameDescriptionExternal IDs
CBLBCbl proto-oncogene B, E3 ubiquitin protein ligase Entrez:868  HPRD: 05136  HGNC: 1542  Ensembl: ENSG00000114423 
ITCHitchy E3 ubiquitin protein ligase Entrez:83737  Ensembl: ENSG00000078747  HGNC: 13890 
CD3ECD3e molecule, epsilon (CD3-TCR complex) Entrez:916  Ensembl: ENSG00000198851  HGNC: 1674  HPRD: 08923 
TGFBR2transforming growth factor, beta receptor II (70/80kDa) Entrez:7048  HGNC: 11773  HPRD: 01823  Ensembl: ENSG00000163513 
FOXP3forkhead box P3 Entrez:50943  HGNC: 6106  HPRD: 02242  Ensembl: ENSG00000049768 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CBLBCbl proto-oncogene B, E3 ubiquitin protein ligase
ITCHitchy E3 ubiquitin protein ligase
CD3ECD3e molecule, epsilon (CD3-TCR complex)
TGFBR2transforming growth factor, beta receptor II (70/80kDa)
FOXP3forkhead box P3
Query geneGeneGene descriptionEdge score
CBLBCBLBCbl proto-oncogene B, E3 ubiquitin protein ligase
ITCHITCHitchy E3 ubiquitin protein ligase
CD3ECD3ECD3e molecule, epsilon (CD3-TCR complex)
TGFBR2TGFBR2transforming growth factor, beta receptor II (70/80kDa)
FOXP3FOXP3forkhead box P3

Troyanskaya Laboratory - Princeton University