ASD

GO:0048489 synaptic vesicle transport (42)

GeneInput weightStandardRank
SYT1--11
SNAP250.25126
VAMP2--33
PCLO--154
SYNJ1--156
AMPH--169
NLGN10.251276
SH3GL2--454
STX1A0.251512
SNCA--1667
STXBP1--769
RIMS10.51777
RAB3A0.251848
DLG4--857
DOC2A0.2511359
CPLX20.2511397
SNPH--1583
ITSN1--1789
UNC13A--1859
SPTBN2--11935
SEPT5--2143
DPYSL2--2672
CPLX1--2778
SYP--3133
CDK50.2513194
OTOF--13498
ZDHHC15--3740
DNM2--14076
CPLX3--4281
TH0.2514933
DDC0.2515929
SLC18A2--6423
OPHN10.516584
CTNNB10.519066
EEA1--10500
UNC13B--13412
MYLK2--113626
STX4--13828
PSEN1--18523
BLOC1S6--21368
DENND1A--22102
SNAPIN--23503

Network

GO:0048489

Network
Enrichment
NameDescriptionExternal IDs
SYT1synaptotagmin I Entrez:6857  HPRD: 01710  HGNC: 11509  Ensembl: ENSG00000067715 
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2) Entrez:6844  HGNC: 12643  HPRD: 01717  Ensembl: ENSG00000220205 
PCLOpiccolo presynaptic cytomatrix protein Entrez:27445  HPRD: 16078  HGNC: 13406  Ensembl: ENSG00000186472 
SYNJ1synaptojanin 1 Entrez:8867  Ensembl: ENSG00000159082  HGNC: 11503  HPRD: 09182 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYT1synaptotagmin I
SNAP25synaptosomal-associated protein, 25kDa
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PCLOpiccolo presynaptic cytomatrix protein
SYNJ1synaptojanin 1
Query geneGeneGene descriptionEdge score
SYT1SYT1synaptotagmin I
SNAP25SNAP25synaptosomal-associated protein, 25kDa
VAMP2VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)
PCLOPCLOpiccolo presynaptic cytomatrix protein
SYNJ1SYNJ1synaptojanin 1

Troyanskaya Laboratory - Princeton University